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Pharmacological mTOR-inhibition facilitates clearance of AD-related tau aggregates in the mouse brain.
Morawe MP, Liao F, Amberg W, van Bergeijk J, Chang R, Gulino M, Hamilton C, Hoft C, Lumpkin C, Mastis B, McGlame E, Nuber J, Plaas C, Ravikumar B, Roy K, Schanzenbächer M, Tierno J, Lakics V, Dellovade T, Townsend M. Morawe MP, et al. Among authors: ravikumar b. Eur J Pharmacol. 2022 Nov 5;934:175301. doi: 10.1016/j.ejphar.2022.175301. Epub 2022 Sep 30. Eur J Pharmacol. 2022. PMID: 36191631 Free article.
Large eQTL meta-analysis reveals differing patterns between cerebral cortical and cerebellar brain regions.
Sieberts SK, Perumal TM, Carrasquillo MM, Allen M, Reddy JS, Hoffman GE, Dang KK, Calley J, Ebert PJ, Eddy J, Wang X, Greenwood AK, Mostafavi S; CommonMind Consortium (CMC); The AMP-AD Consortium; Omberg L, Peters MA, Logsdon BA, De Jager PL, Ertekin-Taner N, Mangravite LM. Sieberts SK, et al. Sci Data. 2020 Oct 12;7(1):340. doi: 10.1038/s41597-020-00642-8. Sci Data. 2020. PMID: 33046718 Free PMC article.
Regulation of mammalian autophagy in physiology and pathophysiology.
Ravikumar B, Sarkar S, Davies JE, Futter M, Garcia-Arencibia M, Green-Thompson ZW, Jimenez-Sanchez M, Korolchuk VI, Lichtenberg M, Luo S, Massey DC, Menzies FM, Moreau K, Narayanan U, Renna M, Siddiqi FH, Underwood BR, Winslow AR, Rubinsztein DC. Ravikumar B, et al. Physiol Rev. 2010 Oct;90(4):1383-435. doi: 10.1152/physrev.00030.2009. Physiol Rev. 2010. PMID: 20959619 Free article. Review.
Dyneins, autophagy, aggregation and neurodegeneration.
Rubinsztein DC, Ravikumar B, Acevedo-Arozena A, Imarisio S, O'Kane CJ, Brown SD. Rubinsztein DC, et al. Among authors: ravikumar b. Autophagy. 2005 Oct-Dec;1(3):177-8. doi: 10.4161/auto.1.3.2050. Epub 2005 Oct 21. Autophagy. 2005. PMID: 16874055 Review.
Plasma membrane helps autophagosomes grow.
Ravikumar B, Moreau K, Rubinsztein DC. Ravikumar B, et al. Autophagy. 2010 Nov;6(8):1184-6. doi: 10.4161/auto.6.8.13428. Epub 2010 Nov 16. Autophagy. 2010. PMID: 20861674 Free PMC article.
108 results