Brüning JC - Search Results

1

Active Akt signaling triggers CLL toward Richter transformation via overactivation of Notch1.

Kohlhaas V, Blakemore SJ, Al-Maarri M, Nickel N, Pal M, Roth A, Hövelmeyer N, Schäfer SC, Knittel G, Lohneis P, Nikolic M, Wiederstein JL, Franitza M, Georgomonolis T, Reinart N, Herling M, Herling C, Hartmann EM, Rosenwald A, Klapper W, Büttner R, Moia R, Rossi D, Boldorini R, Gaidano G, Frenzel LP, Reinhardt HC, Brüning JC, Hallek M, Krüger M, Peifer M, Pallasch CP, Wunderlich FT. Kohlhaas V, et al. Among authors: bruning jc. Blood. 2021 Feb 4;137(5):646-660. doi: 10.1182/blood.2020005734. Blood. 2021. PMID: 33538798 Free article.

2

Transgenic and knockout mice in diabetes research: novel insights into pathophysiology, limitations, and perspectives.

Plum L, Wunderlich FT, Baudler S, Krone W, Brüning JC. Plum L, et al. Among authors: bruning jc. Physiology (Bethesda). 2005 Jun;20:152-61. doi: 10.1152/physiol.00049.2004. Physiology (Bethesda). 2005. PMID: 15888572 Free article. Review.

3

Regulation of B cell homeostasis and activation by the tumor suppressor gene CYLD.

Hövelmeyer N, Wunderlich FT, Massoumi R, Jakobsen CG, Song J, Wörns MA, Merkwirth C, Kovalenko A, Aumailley M, Strand D, Brüning JC, Galle PR, Wallach D, Fässler R, Waisman A. Hövelmeyer N, et al. Among authors: bruning jc. J Exp Med. 2007 Oct 29;204(11):2615-27. doi: 10.1084/jem.20070318. Epub 2007 Oct 8. J Exp Med. 2007. PMID: 17923499 Free PMC article.

4

Enhanced leptin-stimulated Pi3k activation in the CNS promotes white adipose tissue transdifferentiation.

Plum L, Rother E, Münzberg H, Wunderlich FT, Morgan DA, Hampel B, Shanabrough M, Janoschek R, Könner AC, Alber J, Suzuki A, Krone W, Horvath TL, Rahmouni K, Brüning JC. Plum L, et al. Among authors: bruning jc. Cell Metab. 2007 Dec;6(6):431-45. doi: 10.1016/j.cmet.2007.10.012. Cell Metab. 2007. PMID: 18054313 Free article.

5

Hepatic NF-kappa B essential modulator deficiency prevents obesity-induced insulin resistance but synergizes with high-fat feeding in tumorigenesis.

Wunderlich FT, Luedde T, Singer S, Schmidt-Supprian M, Baumgartl J, Schirmacher P, Pasparakis M, Brüning JC. Wunderlich FT, et al. Among authors: bruning jc. Proc Natl Acad Sci U S A. 2008 Jan 29;105(4):1297-302. doi: 10.1073/pnas.0707849104. Epub 2008 Jan 23. Proc Natl Acad Sci U S A. 2008. PMID: 18216263 Free PMC article.

6

Activation of Stat3 signaling in AgRP neurons promotes locomotor activity.

Mesaros A, Koralov SB, Rother E, Wunderlich FT, Ernst MB, Barsh GS, Rajewsky K, Brüning JC. Mesaros A, et al. Among authors: bruning jc. Cell Metab. 2008 Mar;7(3):236-48. doi: 10.1016/j.cmet.2008.01.007. Cell Metab. 2008. PMID: 18316029 Free article.

7

PDK1 deficiency in POMC-expressing cells reveals FOXO1-dependent and -independent pathways in control of energy homeostasis and stress response.

Belgardt BF, Husch A, Rother E, Ernst MB, Wunderlich FT, Hampel B, Klöckener T, Alessi D, Kloppenburg P, Brüning JC. Belgardt BF, et al. Among authors: bruning jc. Cell Metab. 2008 Apr;7(4):291-301. doi: 10.1016/j.cmet.2008.01.006. Cell Metab. 2008. PMID: 18396135 Free article.

8

Central insulin action regulates peripheral glucose and fat metabolism in mice.

Koch L, Wunderlich FT, Seibler J, Könner AC, Hampel B, Irlenbusch S, Brabant G, Kahn CR, Schwenk F, Brüning JC. Koch L, et al. Among authors: bruning jc. J Clin Invest. 2008 Jun;118(6):2132-47. doi: 10.1172/JCI31073. J Clin Invest. 2008. PMID: 18451994 Free PMC article.

9

Epidermal insulin/IGF-1 signalling control interfollicular morphogenesis and proliferative potential through Rac activation.

Stachelscheid H, Ibrahim H, Koch L, Schmitz A, Tscharntke M, Wunderlich FT, Scott J, Michels C, Wickenhauser C, Haase I, Brüning JC, Niessen CM. Stachelscheid H, et al. Among authors: bruning jc. EMBO J. 2008 Aug 6;27(15):2091-101. doi: 10.1038/emboj.2008.141. Epub 2008 Jul 24. EMBO J. 2008. PMID: 18650937 Free PMC article.

10

Secondary consequences of beta cell inexcitability: identification and prevention in a murine model of K(ATP)-induced neonatal diabetes mellitus.

Remedi MS, Kurata HT, Scott A, Wunderlich FT, Rother E, Kleinridders A, Tong A, Brüning JC, Koster JC, Nichols CG. Remedi MS, et al. Among authors: bruning jc. Cell Metab. 2009 Feb;9(2):140-51. doi: 10.1016/j.cmet.2008.12.005. Cell Metab. 2009. PMID: 19187772 Free PMC article.

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