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Active Akt signaling triggers CLL toward Richter transformation via overactivation of Notch1.
Kohlhaas V, Blakemore SJ, Al-Maarri M, Nickel N, Pal M, Roth A, Hövelmeyer N, Schäfer SC, Knittel G, Lohneis P, Nikolic M, Wiederstein JL, Franitza M, Georgomonolis T, Reinart N, Herling M, Herling C, Hartmann EM, Rosenwald A, Klapper W, Büttner R, Moia R, Rossi D, Boldorini R, Gaidano G, Frenzel LP, Reinhardt HC, Brüning JC, Hallek M, Krüger M, Peifer M, Pallasch CP, Wunderlich FT. Kohlhaas V, et al. Among authors: frenzel lp. Blood. 2021 Feb 4;137(5):646-660. doi: 10.1182/blood.2020005734. Blood. 2021. PMID: 33538798 Free article.
miRNA deregulation by epigenetic silencing disrupts suppression of the oncogene PLAG1 in chronic lymphocytic leukemia.
Pallasch CP, Patz M, Park YJ, Hagist S, Eggle D, Claus R, Debey-Pascher S, Schulz A, Frenzel LP, Claasen J, Kutsch N, Krause G, Mayr C, Rosenwald A, Plass C, Schultze JL, Hallek M, Wendtner CM. Pallasch CP, et al. Among authors: frenzel lp. Blood. 2009 Oct 8;114(15):3255-64. doi: 10.1182/blood-2009-06-229898. Epub 2009 Aug 19. Blood. 2009. PMID: 19692702 Free PMC article.
Rapid generation of human B-cell lymphomas via combined expression of Myc and Bcl2 and their use as a preclinical model for biological therapies.
Leskov I, Pallasch CP, Drake A, Iliopoulou BP, Souza A, Shen CH, Schweighofer CD, Abruzzo L, Frenzel LP, Wendtner CM, Hemann MT, Chen J. Leskov I, et al. Among authors: frenzel lp. Oncogene. 2013 Feb 21;32(8):1066-1072. doi: 10.1038/onc.2012.117. Epub 2012 Apr 9. Oncogene. 2013. PMID: 22484426 Free PMC article.
43 results