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Identification and Therapeutic Targeting of GPR20, Selectively Expressed in Gastrointestinal Stromal Tumors, with DS-6157a, a First-in-Class Antibody-Drug Conjugate.
Iida K, Abdelhamid Ahmed AH, Nagatsuma AK, Shibutani T, Yasuda S, Kitamura M, Hattori C, Abe M, Hasegawa J, Iguchi T, Karibe T, Nakada T, Inaki K, Kamei R, Abe Y, Nomura T, Andersen JL, Santagata S, Hemming ML, George S, Doi T, Ochiai A, Demetri GD, Agatsuma T. Iida K, et al. Among authors: kitamura m. Cancer Discov. 2021 Jun;11(6):1508-1523. doi: 10.1158/2159-8290.CD-20-1434. Epub 2021 Feb 12. Cancer Discov. 2021. PMID: 33579785 Clinical Trial.
Datopotamab Deruxtecan, a Novel TROP2-directed Antibody-drug Conjugate, Demonstrates Potent Antitumor Activity by Efficient Drug Delivery to Tumor Cells.
Okajima D, Yasuda S, Maejima T, Karibe T, Sakurai K, Aida T, Toki T, Yamaguchi J, Kitamura M, Kamei R, Fujitani T, Honda T, Shibutani T, Muramatsu S, Nakada T, Goto R, Takahashi S, Yamaguchi M, Hamada H, Noguchi Y, Murakami M, Abe Y, Agatsuma T. Okajima D, et al. Among authors: kitamura m. Mol Cancer Ther. 2021 Dec;20(12):2329-2340. doi: 10.1158/1535-7163.MCT-21-0206. Epub 2021 Aug 19. Mol Cancer Ther. 2021. PMID: 34413126 Free PMC article.
Wide application of a novel topoisomerase I inhibitor-based drug conjugation technology.
Ogitani Y, Abe Y, Iguchi T, Yamaguchi J, Terauchi T, Kitamura M, Goto K, Goto M, Oitate M, Yukinaga H, Yabe Y, Nakada T, Masuda T, Morita K, Agatsuma T. Ogitani Y, et al. Among authors: kitamura m. Bioorg Med Chem Lett. 2016 Oct 15;26(20):5069-5072. doi: 10.1016/j.bmcl.2016.08.082. Epub 2016 Aug 27. Bioorg Med Chem Lett. 2016. PMID: 27599744
Novel anti-EPHA2 antibody, DS-8895a for cancer treatment.
Hasegawa J, Sue M, Yamato M, Ichikawa J, Ishida S, Shibutani T, Kitamura M, Wada T, Agatsuma T. Hasegawa J, et al. Among authors: kitamura m. Cancer Biol Ther. 2016 Nov;17(11):1158-1167. doi: 10.1080/15384047.2016.1235663. Epub 2016 Sep 21. Cancer Biol Ther. 2016. PMID: 27653549 Free PMC article.
Renin-angiotensin system inhibitors for patients with mild or moderate chronic kidney disease and heart failure with mildly reduced or preserved ejection fraction.
Takeuchi S, Kohno T, Goda A, Shiraishi Y, Kitamura M, Nagatomo Y, Takei M, Nomoto M, Soejima K, Kohsaka S, Yoshikawa T; West Tokyo Heart Failure Registry Investigators. Takeuchi S, et al. Among authors: kitamura m. Int J Cardiol. 2024 May 16;409:132190. doi: 10.1016/j.ijcard.2024.132190. Online ahead of print. Int J Cardiol. 2024. PMID: 38761975
Supra-normal and mildly reduced ejection fraction in women -An overlooked vulnerable subpopulation in heart failure.
Kawai A, Nagatomo Y, Yukino-Iwashita M, Ikegami Y, Takei M, Goda A, Kohno T, Mizuno A, Kitamura M, Nakano S, Sakamoto M, Shiraishi Y, Kohsaka S, Adachi T, Yoshikawa T; as WET-HF investigators. Kawai A, et al. Among authors: kitamura m. Int J Cardiol. 2024 May 12;409:132166. doi: 10.1016/j.ijcard.2024.132166. Online ahead of print. Int J Cardiol. 2024. PMID: 38744340
ALBI score predicts morphological changes in esophageal varices following direct-acting antiviral-induced sustained virological response in patients with liver cirrhosis.
Atsukawa M, Tsubota A, Kondo C, Toyoda H, Takaguchi K, Nakamuta M, Watanabe T, Morishita A, Tani J, Okubo H, Hiraoka A, Nozaki A, Chuma M, Kawata K, Uojima H, Ogawa C, Asano T, Mikami S, Kato K, Matsuura K, Ikegami T, Ishikawa T, Tsuji K, Tada T, Tsutsui A, Senoh T, Kitamura M, Okubo T, Arai T, Kohjima M, Morita K, Akahane T, Nishikawa H, Iwasa M, Tanaka Y, Iwakiri K. Atsukawa M, et al. Among authors: kitamura m. J Gastroenterol. 2024 May 10. doi: 10.1007/s00535-024-02109-8. Online ahead of print. J Gastroenterol. 2024. PMID: 38727822
Renal tubular necrosis associated with anagrelide administration: a case report.
Sawase A, Kitamura M, Morimoto M, Fukuda H, Uramatsu T, Katafuchi E, Yamashita H, Nakayama T, Mukae H, Nishino T. Sawase A, et al. Among authors: kitamura m. CEN Case Rep. 2024 Apr 24. doi: 10.1007/s13730-024-00881-3. Online ahead of print. CEN Case Rep. 2024. PMID: 38658458 Free article.
1,871 results