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Next-generation XPO1 inhibitor shows improved efficacy and in vivo tolerability in hematological malignancies.
Hing ZA, Fung HY, Ranganathan P, Mitchell S, El-Gamal D, Woyach JA, Williams K, Goettl VM, Smith J, Yu X, Meng X, Sun Q, Cagatay T, Lehman AM, Lucas DM, Baloglu E, Shacham S, Kauffman MG, Byrd JC, Chook YM, Garzon R, Lapalombella R. Hing ZA, et al. Among authors: cagatay t. Leukemia. 2016 Dec;30(12):2364-2372. doi: 10.1038/leu.2016.136. Epub 2016 May 20. Leukemia. 2016. PMID: 27323910 Free PMC article.
Karyopherins in cancer.
Çağatay T, Chook YM. Çağatay T, et al. Curr Opin Cell Biol. 2018 Jun;52:30-42. doi: 10.1016/j.ceb.2018.01.006. Epub 2018 Feb 4. Curr Opin Cell Biol. 2018. PMID: 29414591 Free PMC article. Review.
Correlation of CRM1-NES affinity with nuclear export activity.
Fu SC, Fung HYJ, Cağatay T, Baumhardt J, Chook YM. Fu SC, et al. Among authors: cagatay t. Mol Biol Cell. 2018 Aug 15;29(17):2037-2044. doi: 10.1091/mbc.E18-02-0096. Epub 2018 Jun 21. Mol Biol Cell. 2018. PMID: 29927350 Free PMC article.
Nuclear speckle integrity and function require TAO2 kinase.
Gao S, Esparza M, Dehghan I, Aksenova V, Zhang K, Batten K, Ferretti MB, Begg BE, Cagatay T, Shay JW, García-Sastre A, Goldsmith EJ, Chen ZJ, Dasso M, Lynch KW, Cobb MH, Fontoura BMA. Gao S, et al. Among authors: cagatay t. Proc Natl Acad Sci U S A. 2022 Jun 21;119(25):e2206046119. doi: 10.1073/pnas.2206046119. Epub 2022 Jun 15. Proc Natl Acad Sci U S A. 2022. PMID: 35704758 Free PMC article.
49 results