Kwak SH - Search Results

1

Synthesis and evaluation of cyclopentane-based muraymycin analogs targeting MraY.

Kwak SH, Lim WY, Hao A, Mashalidis EH, Kwon DY, Jeong P, Kim MJ, Lee SY, Hong J. Kwak SH, et al. Eur J Med Chem. 2021 Apr 5;215:113272. doi: 10.1016/j.ejmech.2021.113272. Epub 2021 Feb 6. Eur J Med Chem. 2021. PMID: 33607457 Free PMC article.

2

Synthesis and structure-activity relationships of quinolinone and quinoline-based P2X7 receptor antagonists and their anti-sphere formation activities in glioblastoma cells.

Kwak SH, Shin S, Lee JH, Shim JK, Kim M, Lee SD, Lee A, Bae J, Park JH, Abdelrahman A, Müller CE, Cho SK, Kang SG, Bae MA, Yang JY, Ko H, Goddard WA 3rd, Kim YC. Kwak SH, et al. Eur J Med Chem. 2018 May 10;151:462-481. doi: 10.1016/j.ejmech.2018.03.023. Epub 2018 Mar 9. Eur J Med Chem. 2018. PMID: 29649742

3

Structure-Activity Relationship of Sulfonyl Piperazine LpxH Inhibitors Analyzed by an LpxE-Coupled Malachite Green Assay.

Lee M, Zhao J, Kwak SH, Cho J, Lee M, Gillespie RA, Kwon DY, Lee H, Park HJ, Wu Q, Zhou P, Hong J. Lee M, et al. Among authors: kwak sh. ACS Infect Dis. 2019 Apr 12;5(4):641-651. doi: 10.1021/acsinfecdis.8b00364. Epub 2019 Feb 5. ACS Infect Dis. 2019. PMID: 30721024 Free PMC article.

4

Evaluation of Manassantin A Tetrahydrofuran Core Region Analogues and Cooperative Therapeutic Effects with EGFR Inhibition.

Kwak SH, Stephenson TN, Lee HE, Ge Y, Lee H, Min SM, Kim JH, Kwon DY, Lee YM, Hong J. Kwak SH, et al. J Med Chem. 2020 Jul 9;63(13):6821-6833. doi: 10.1021/acs.jmedchem.0c00151. Epub 2020 Jun 24. J Med Chem. 2020. PMID: 32579356

5

Synthesis and evaluation of sulfonyl piperazine LpxH inhibitors.

Kwak SH, Cochrane CS, Ennis AF, Lim WY, Webster CG, Cho J, Fenton BA, Zhou P, Hong J. Kwak SH, et al. Bioorg Chem. 2020 Sep;102:104055. doi: 10.1016/j.bioorg.2020.104055. Epub 2020 Jun 30. Bioorg Chem. 2020. PMID: 32663666 Free PMC article.

6

Discovery and structure-activity relationship studies of quinolinone derivatives as potent IL-2 suppressive agents.

Kwak SH, Kang JA, Kim M, Lee SD, Park JH, Park SG, Ko H, Kim YC. Kwak SH, et al. Bioorg Med Chem. 2016 Nov 1;24(21):5357-5367. doi: 10.1016/j.bmc.2016.08.051. Epub 2016 Aug 29. Bioorg Med Chem. 2016. PMID: 27647370

7

Escape from adamantane: Scaffold optimization of novel P2X7 antagonists featuring complex polycycles.

Barniol-Xicota M, Kwak SH, Lee SD, Caseley E, Valverde E, Jiang LH, Kim YC, Vázquez S. Barniol-Xicota M, et al. Among authors: kwak sh. Bioorg Med Chem Lett. 2017 Feb 15;27(4):759-763. doi: 10.1016/j.bmcl.2017.01.039. Epub 2017 Jan 16. Bioorg Med Chem Lett. 2017. PMID: 28126517 Free article.

8

Discovery of 3-Phenyl Indazole-Based Novel Chemokine-like Receptor 1 Antagonists for the Treatment of Psoriasis.

Ko B, Jang Y, Kwak SH, You H, Kim JH, Lee JE, Park HD, Kim SK, Goddard WA 3rd, Han JH, Kim YC. Ko B, et al. Among authors: kwak sh. J Med Chem. 2023 Nov 9;66(21):14564-14582. doi: 10.1021/acs.jmedchem.3c01011. Epub 2023 Oct 26. J Med Chem. 2023. PMID: 37883692

9

Discovery of novel purine-based heterocyclic P2X7 receptor antagonists.

Kwak SH, Lee WG, Lee YJ, Lee SD, Kim YC, Ko H. Kwak SH, et al. Bioorg Chem. 2015 Aug;61:58-65. doi: 10.1016/j.bioorg.2015.06.003. Epub 2015 Jun 20. Bioorg Chem. 2015. PMID: 26123174

10

Development and validation of an interpretable model for predicting sepsis mortality across care settings.

Lee YS, Han S, Lee YE, Cho J, Choi YK, Yoon SY, Oh DK, Lee SY, Park MH, Lim CM, Moon JY; Korean Sepsis Alliance (KSA) Investigators. Lee YS, et al. Sci Rep. 2024 Jun 13;14(1):13637. doi: 10.1038/s41598-024-64463-0. Sci Rep. 2024. PMID: 38871785 Free PMC article.

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