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Small-Molecule Activation of Protein Phosphatase 2A Counters Bleomycin-Induced Fibrosis in Mice.
Pillai M, Lafortune P, Dabo A, Yu H, Park SS, Taluru H, Ahmed H, Bobrow D, Sattar Z, Jundi B, Reece J, Ortega RR, Soto B, Yewedalsew S, Foronjy R, Wyman A, Geraghty P, Ohlmeyer M. Pillai M, et al. Among authors: ohlmeyer m. ACS Pharmacol Transl Sci. 2023 Oct 17;6(11):1659-1672. doi: 10.1021/acsptsci.3c00117. eCollection 2023 Nov 10. ACS Pharmacol Transl Sci. 2023. PMID: 37974628
Protein Phosphatase 2A as a Therapeutic Target in Pulmonary Diseases.
Yu H, Zaveri S, Sattar Z, Schaible M, Perez Gandara B, Uddin A, McGarvey LR, Ohlmeyer M, Geraghty P. Yu H, et al. Among authors: ohlmeyer m. Medicina (Kaunas). 2023 Aug 26;59(9):1552. doi: 10.3390/medicina59091552. Medicina (Kaunas). 2023. PMID: 37763671 Free PMC article. Review.
Evaluating Novel Protein Phosphatase 2A Activators as Therapeutics for Emphysema.
Soto B, Ahmed H, Pillai M, Park SS, Ploszaj M, Reece J, Taluru H, Bobrow D, Yu H, Lafortune P, Jundi B, Costanzo L, Dabo AJ, Foronjy RF, Mueller C, Ohlmeyer M, Geraghty P. Soto B, et al. Among authors: ohlmeyer m. Am J Respir Cell Mol Biol. 2023 Nov;69(5):533-544. doi: 10.1165/rcmb.2023-0105OC. Am J Respir Cell Mol Biol. 2023. PMID: 37526463
PP2A-based triple-strike therapy overcomes mitochondrial apoptosis resistance in brain cancer cells.
Denisova OV, Merisaari J, Huhtaniemi R, Qiao X, Yetukuri L, Jumppanen M, Kaur A, Pääkkönen M, von Schantz-Fant С, Ohlmeyer M, Wennerberg K, Kauko O, Koch R, Aittokallio T, Taipale M, Westermarck J. Denisova OV, et al. Among authors: ohlmeyer m. Mol Oncol. 2023 Sep;17(9):1803-1820. doi: 10.1002/1878-0261.13488. Epub 2023 Jul 26. Mol Oncol. 2023. PMID: 37458534 Free PMC article.
Rapid Characterization of Solid Tumors Using Resonant Sensors.
Beierle AM, Quinn CH, Markert HR, Carr A, Marayati R, Bownes LV, Hutchins SC, Stewart JE, Hill B, Ohlmeyer M, Reuel NF, Beierle EA. Beierle AM, et al. Among authors: ohlmeyer m. ACS Omega. 2022 Sep 2;7(36):32690-32700. doi: 10.1021/acsomega.2c04345. eCollection 2022 Sep 13. ACS Omega. 2022. PMID: 36119978 Free PMC article.
Development of actionable targets of multi-kinase inhibitors (AToMI) screening platform to dissect kinase targets of staurosporines in glioblastoma cells.
Denisova OV, Merisaari J, Kaur A, Yetukuri L, Jumppanen M, von Schantz-Fant C, Ohlmeyer M, Wennerberg K, Aittokallio T, Taipale M, Westermarck J. Denisova OV, et al. Among authors: ohlmeyer m. Sci Rep. 2022 Aug 13;12(1):13796. doi: 10.1038/s41598-022-18118-7. Sci Rep. 2022. PMID: 35963891 Free PMC article.
T-cell exhaustion induced by continuous bispecific molecule exposure is ameliorated by treatment-free intervals.
Philipp N, Kazerani M, Nicholls A, Vick B, Wulf J, Straub T, Scheurer M, Muth A, Hänel G, Nixdorf D, Sponheimer M, Ohlmeyer M, Lacher SM, Brauchle B, Marcinek A, Rohrbacher L, Leutbecher A, Rejeski K, Weigert O, von Bergwelt-Baildon M, Theurich S, Kischel R, Jeremias I, Bücklein V, Subklewe M. Philipp N, et al. Among authors: ohlmeyer m. Blood. 2022 Sep 8;140(10):1104-1118. doi: 10.1182/blood.2022015956. Blood. 2022. PMID: 35878001 Free PMC article.
TBK1 and IKKε act like an OFF switch to limit NLRP3 inflammasome pathway activation.
Fischer FA, Mies LFM, Nizami S, Pantazi E, Danielli S, Demarco B, Ohlmeyer M, Lee MSJ, Coban C, Kagan JC, Di Daniel E, Bezbradica JS. Fischer FA, et al. Among authors: ohlmeyer m. Proc Natl Acad Sci U S A. 2021 Sep 21;118(38):e2009309118. doi: 10.1073/pnas.2009309118. Proc Natl Acad Sci U S A. 2021. PMID: 34518217 Free PMC article.
58 results