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Pre-conditioning modifies the TME to enhance solid tumor CAR T cell efficacy and endogenous protective immunity.
Mol Ther. 2021 Jul 7;29(7):2335-2349. doi: 10.1016/j.ymthe.2021.02.024. Epub 2021 Feb 27.
Mol Ther. 2021.
PMID: 33647456
Free PMC article.
Large-scale manufacturing and characterization of CMV-CD19CAR T cells.
Wang X, Urak R, Walter M, Guan M, Han T, Vyas V, Chien SH, Gittins B, Clark MC, Mokhtari S, Cardoso A, Diamond DJ, Zaia J, Forman SJ, Nakamura R.
Wang X, et al.
J Immunother Cancer. 2022 Jan;10(1):e003461. doi: 10.1136/jitc-2021-003461.
J Immunother Cancer. 2022.
PMID: 35027426
Free PMC article.
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Antigen-dependent IL-12 signaling in CAR T cells promotes regional to systemic disease targeting.
Jun Lee EH, Cullen C, Murad JP, Gumber D, Park AK, Yang J, Stern LA, Adkins LN, Dhapola G, Gittins B, Chung-Chang W, Martinez C, Woo Y, Cristea M, Rodriguez-Rodriguez L, Ishihara J, Lee JK, Forman SJ, Wang LD, Priceman SJ.
Jun Lee EH, et al.
bioRxiv [Preprint]. 2023 Jan 7:2023.01.06.522784. doi: 10.1101/2023.01.06.522784.
bioRxiv. 2023.
Update in:
Nat Commun. 2023 Aug 7;14(1):4737. doi: 10.1038/s41467-023-40115-1.
PMID: 36711615
Free PMC article.
Updated.
Preprint.
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Evaluation of the Elements of Short Hairpin RNAs in Developing shRNA-Containing CAR T Cells.
Urak R, Gittins B, Soemardy C, Grepo N, Goldberg L, Maker M, Shevchenko G, Davis A, Li S, Scott T, Morris KV, Forman SJ, Wang X.
Urak R, et al.
Cancers (Basel). 2023 May 20;15(10):2848. doi: 10.3390/cancers15102848.
Cancers (Basel). 2023.
PMID: 37345185
Free PMC article.
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Antigen-dependent IL-12 signaling in CAR T cells promotes regional to systemic disease targeting.
Lee EHJ, Murad JP, Christian L, Gibson J, Yamaguchi Y, Cullen C, Gumber D, Park AK, Young C, Monroy I, Yang J, Stern LA, Adkins LN, Dhapola G, Gittins B, Chang WC, Martinez C, Woo Y, Cristea M, Rodriguez-Rodriguez L, Ishihara J, Lee JK, Forman SJ, Wang LD, Priceman SJ.
Lee EHJ, et al.
Nat Commun. 2023 Aug 7;14(1):4737. doi: 10.1038/s41467-023-40115-1.
Nat Commun. 2023.
PMID: 37550294
Free PMC article.
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Simultaneous targeting of B-cell malignancies and human immunodeficiency virus with bispecific chimeric antigen receptor T cells.
Urak R, Pahlavanneshan S, Gittins B, Nakamura R, Zaia JA, Baird JH, Clark MC, Forman SJ, Wang X.
Urak R, et al.
Haematologica. 2024 May 23. doi: 10.3324/haematol.2024.285321. Online ahead of print.
Haematologica. 2024.
PMID: 38779743
Free article.
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