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Structural Basis for Accommodation of Emerging B.1.351 and B.1.1.7 Variants by Two Potent SARS-CoV-2 Neutralizing Antibodies.
Cerutti G, Rapp M, Guo Y, Bahna F, Bimela J, Reddem ER, Yu J, Wang P, Liu L, Huang Y, Ho DD, Kwong PD, Sheng Z, Shapiro L. Cerutti G, et al. Among authors: kwong pd. bioRxiv [Preprint]. 2021 Feb 22:2021.02.21.432168. doi: 10.1101/2021.02.21.432168. bioRxiv. 2021. Update in: Structure. 2021 Jul 1;29(7):655-663.e4. doi: 10.1016/j.str.2021.05.014. PMID: 33655245 Free PMC article. Updated. Preprint.
Vaccine design reaches the atomic level.
Kwong PD, Shapiro L. Kwong PD, et al. Sci Transl Med. 2011 Jul 13;3(91):91ps29. doi: 10.1126/scitranslmed.3002807. Sci Transl Med. 2011. PMID: 21753119 Free PMC article.
Targeted Isolation of Antibodies Directed against Major Sites of SIV Env Vulnerability.
Mason RD, Welles HC, Adams C, Chakrabarti BK, Gorman J, Zhou T, Nguyen R, O'Dell S, Lusvarghi S, Bewley CA, Li H, Shaw GM, Sheng Z, Shapiro L, Wyatt R, Kwong PD, Mascola JR, Roederer M. Mason RD, et al. Among authors: kwong pd. PLoS Pathog. 2016 Apr 11;12(4):e1005537. doi: 10.1371/journal.ppat.1005537. eCollection 2016 Apr. PLoS Pathog. 2016. PMID: 27064278 Free PMC article.
Structural Survey of Broadly Neutralizing Antibodies Targeting the HIV-1 Env Trimer Delineates Epitope Categories and Characteristics of Recognition.
Chuang GY, Zhou J, Acharya P, Rawi R, Shen CH, Sheng Z, Zhang B, Zhou T, Bailer RT, Dandey VP, Doria-Rose NA, Louder MK, McKee K, Mascola JR, Shapiro L, Kwong PD. Chuang GY, et al. Among authors: kwong pd. Structure. 2019 Jan 2;27(1):196-206.e6. doi: 10.1016/j.str.2018.10.007. Epub 2018 Nov 21. Structure. 2019. PMID: 30471922 Free PMC article.
Potent Neutralizing Antibodies Directed to Multiple Epitopes on SARS-CoV-2 Spike.
Liu L, Wang P, Nair MS, Yu J, Rapp M, Wang Q, Luo Y, Chan JF, Sahi V, Figueroa A, Guo XV, Cerutti G, Bimela J, Gorman J, Zhou T, Chen Z, Yuen KY, Kwong PD, Sodroski JG, Yin MT, Sheng Z, Huang Y, Shapiro L, Ho DD. Liu L, et al. Among authors: kwong pd. bioRxiv [Preprint]. 2020 Jul 16:2020.06.17.153486. doi: 10.1101/2020.06.17.153486. bioRxiv. 2020. Update in: Nature. 2020 Aug;584(7821):450-456. doi: 10.1038/s41586-020-2571-7. PMID: 32587975 Free PMC article. Updated. Preprint.
Structure-Based Design with Tag-Based Purification and In-Process Biotinylation Enable Streamlined Development of SARS-CoV-2 Spike Molecular Probes.
Zhou T, Teng IT, Olia AS, Cerutti G, Gorman J, Nazzari A, Shi W, Tsybovsky Y, Wang L, Wang S, Zhang B, Zhang Y, Katsamba PS, Petrova Y, Banach BB, Fahad AS, Liu L, Lopez Acevedo SN, Madan B, de Souza MO, Pan X, Wang P, Wolfe JR, Yin M, Ho DD, Phung E, DiPiazza A, Chang L, Abiona O, Corbett KS, DeKosky BJ, Graham BS, Mascola JR, Misasi J, Ruckwardt T, Sullivan NJ, Shapiro L, Kwong PD. Zhou T, et al. Among authors: kwong pd. bioRxiv [Preprint]. 2020 Jun 23:2020.06.22.166033. doi: 10.1101/2020.06.22.166033. bioRxiv. 2020. Update in: Cell Rep. 2020 Oct 27;33(4):108322. doi: 10.1016/j.celrep.2020.108322. PMID: 32596696 Free PMC article. Updated. Preprint.
Cryo-EM Structures Delineate a pH-Dependent Switch that Mediates Endosomal Positioning of SARS-CoV-2 Spike Receptor-Binding Domains.
Zhou T, Tsybovsky Y, Olia AS, Gorman J, Rapp MA, Cerutti G, Chuang GY, Katsamba PS, Nazzari A, Sampson JM, Schon A, Wang PD, Bimela J, Shi W, Teng IT, Zhang B, Boyington JC, Sastry M, Stephens T, Stuckey J, Wang S, Friesner RA, Ho DD, Mascola JR, Shapiro L, Kwong PD. Zhou T, et al. Among authors: kwong pd. bioRxiv [Preprint]. 2020 Jul 31:2020.07.04.187989. doi: 10.1101/2020.07.04.187989. bioRxiv. 2020. Update in: Cell Host Microbe. 2020 Dec 9;28(6):867-879.e5. doi: 10.1016/j.chom.2020.11.004. PMID: 32637958 Free PMC article. Updated. Preprint.
455 results