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Cannabidiol Enhances Intestinal Cannabinoid Receptor Type 2 Receptor Expression and Activation Increasing Regulatory T Cells and Reduces Murine Acute Graft-versus-Host Disease without Interfering with the Graft-versus-Leukemia Response.
Berg BB, Soares JS, Paiva IR, Rezende BM, Rachid MA, Cau SBA, Romero TRL, Pinho V, Teixeira MM, Castor MGME. Berg BB, et al. Among authors: castor mgme. J Pharmacol Exp Ther. 2021 May;377(2):273-283. doi: 10.1124/jpet.120.000479. Epub 2021 Mar 3. J Pharmacol Exp Ther. 2021. PMID: 33658314
Inhibition of 5-lipoxygenase alleviates graft-versus-host disease.
Rezende BM, Athayde RM, Gonçalves WA, Resende CB, Teles de Tolêdo Bernardes P, Perez DA, Esper L, Reis AC, Rachid MA, Castor MGME, Cunha TM, Machado FS, Teixeira MM, Pinho V. Rezende BM, et al. J Exp Med. 2017 Nov 6;214(11):3399-3415. doi: 10.1084/jem.20170261. Epub 2017 Sep 25. J Exp Med. 2017. PMID: 28947611 Free PMC article.
Evidence for the involvement of opioid and cannabinoid systems in the peripheral antinociception mediated by resveratrol.
Oliveira CDC, Castor MGME, Castor CGME, Costa ÁF, Ferreira RCM, Silva JFD, Pelaez JMN, Capettini LDSA, Lemos VS, Duarte IDG, Perez AC, Santos SHS, Romero TRL. Oliveira CDC, et al. Among authors: castor mgme. Toxicol Appl Pharmacol. 2019 Apr 15;369:30-38. doi: 10.1016/j.taap.2019.02.004. Epub 2019 Feb 11. Toxicol Appl Pharmacol. 2019. PMID: 30763598
Anandamide reduces the migration of lymphocytes to the intestine by CB2 activation and reduces TNF-α in the target organs, protecting mice from graft-versus-host disease.
Berg BB, Linhares AFS, Martins DM, Rachid MA, Cau SBA, Souza GG, Carvalho JCS, Sorgi CA, Romero TRL, Pinho V, Teixeira MM, Castor MGME. Berg BB, et al. Among authors: castor mgme. Eur J Pharmacol. 2023 Oct 5;956:175932. doi: 10.1016/j.ejphar.2023.175932. Epub 2023 Aug 1. Eur J Pharmacol. 2023. PMID: 37536622
23 results