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P-selectin deficiency attenuates tumor growth and metastasis.
Kim YJ, Borsig L, Varki NM, Varki A. Kim YJ, et al. Among authors: varki a, varki nm. Proc Natl Acad Sci U S A. 1998 Aug 4;95(16):9325-30. doi: 10.1073/pnas.95.16.9325. Proc Natl Acad Sci U S A. 1998. PMID: 9689079 Free PMC article.
Synergistic effects of L- and P-selectin in facilitating tumor metastasis can involve non-mucin ligands and implicate leukocytes as enhancers of metastasis.
Borsig L, Wong R, Hynes RO, Varki NM, Varki A. Borsig L, et al. Among authors: varki a, varki nm. Proc Natl Acad Sci U S A. 2002 Feb 19;99(4):2193-8. doi: 10.1073/pnas.261704098. Proc Natl Acad Sci U S A. 2002. PMID: 11854515 Free PMC article.
P-selectin facilitates human carcinoma metastasis in immunodeficient mice by mediating early interactions of platelets with bloodborne tumor cells via their cell surface mucins, and this process can be blocked by heparin [Borsig, L., Wong, R., Feramisco, J., Nadeau, D. R., Var
P-selectin facilitates human carcinoma metastasis in immunodeficient mice by mediating early interactions of platelets with bloodborne tumor …
Human uptake and incorporation of an immunogenic nonhuman dietary sialic acid.
Tangvoranuntakul P, Gagneux P, Diaz S, Bardor M, Varki N, Varki A, Muchmore E. Tangvoranuntakul P, et al. Among authors: varki a, varki n. Proc Natl Acad Sci U S A. 2003 Oct 14;100(21):12045-50. doi: 10.1073/pnas.2131556100. Epub 2003 Oct 1. Proc Natl Acad Sci U S A. 2003. PMID: 14523234 Free PMC article.
Loss of Siglec expression on T lymphocytes during human evolution.
Nguyen DH, Hurtado-Ziola N, Gagneux P, Varki A. Nguyen DH, et al. Among authors: varki a. Proc Natl Acad Sci U S A. 2006 May 16;103(20):7765-70. doi: 10.1073/pnas.0510484103. Epub 2006 May 8. Proc Natl Acad Sci U S A. 2006. PMID: 16682635 Free PMC article.
559 results