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Application of niclosamide and analogs as small molecule inhibitors of Zika virus and SARS-CoV-2 infection.
Shamim K, Xu M, Hu X, Lee EM, Lu X, Huang R, Shah P, Xu X, Chen CZ, Shen M, Guo H, Chen L, Itkin Z, Eastman RT, Shinn P, Klumpp-Thomas C, Michael S, Simeonov A, Lo DC, Ming GL, Song H, Tang H, Zheng W, Huang W. Shamim K, et al. Among authors: lee em. Bioorg Med Chem Lett. 2021 May 15;40:127906. doi: 10.1016/j.bmcl.2021.127906. Epub 2021 Mar 6. Bioorg Med Chem Lett. 2021. PMID: 33689873 Free PMC article.
Cyclophilins as modulators of viral replication.
Frausto SD, Lee E, Tang H. Frausto SD, et al. Viruses. 2013 Jul 11;5(7):1684-701. doi: 10.3390/v5071684. Viruses. 2013. PMID: 23852270 Free PMC article. Review.
Zika Virus Infects Human Cortical Neural Progenitors and Attenuates Their Growth.
Tang H, Hammack C, Ogden SC, Wen Z, Qian X, Li Y, Yao B, Shin J, Zhang F, Lee EM, Christian KM, Didier RA, Jin P, Song H, Ming GL. Tang H, et al. Among authors: lee em. Cell Stem Cell. 2016 May 5;18(5):587-90. doi: 10.1016/j.stem.2016.02.016. Epub 2016 Mar 4. Cell Stem Cell. 2016. PMID: 26952870 Free PMC article.
Identification of small-molecule inhibitors of Zika virus infection and induced neural cell death via a drug repurposing screen.
Xu M, Lee EM, Wen Z, Cheng Y, Huang WK, Qian X, Tcw J, Kouznetsova J, Ogden SC, Hammack C, Jacob F, Nguyen HN, Itkin M, Hanna C, Shinn P, Allen C, Michael SG, Simeonov A, Huang W, Christian KM, Goate A, Brennand KJ, Huang R, Xia M, Ming GL, Zheng W, Song H, Tang H. Xu M, et al. Among authors: lee em. Nat Med. 2016 Oct;22(10):1101-1107. doi: 10.1038/nm.4184. Epub 2016 Aug 29. Nat Med. 2016. PMID: 27571349 Free PMC article.
Molecular signatures associated with ZIKV exposure in human cortical neural progenitors.
Zhang F, Hammack C, Ogden SC, Cheng Y, Lee EM, Wen Z, Qian X, Nguyen HN, Li Y, Yao B, Xu M, Xu T, Chen L, Wang Z, Feng H, Huang WK, Yoon KJ, Shan C, Huang L, Qin Z, Christian KM, Shi PY, Xu M, Xia M, Zheng W, Wu H, Song H, Tang H, Ming GL, Jin P. Zhang F, et al. Among authors: lee em. Nucleic Acids Res. 2016 Oct 14;44(18):8610-8620. doi: 10.1093/nar/gkw765. Epub 2016 Aug 31. Nucleic Acids Res. 2016. PMID: 27580721 Free PMC article.
Zika virus directly infects peripheral neurons and induces cell death.
Oh Y, Zhang F, Wang Y, Lee EM, Choi IY, Lim H, Mirakhori F, Li R, Huang L, Xu T, Wu H, Li C, Qin CF, Wen Z, Wu QF, Tang H, Xu Z, Jin P, Song H, Ming GL, Lee G. Oh Y, et al. Among authors: lee g, lee em. Nat Neurosci. 2017 Sep;20(9):1209-1212. doi: 10.1038/nn.4612. Epub 2017 Jul 31. Nat Neurosci. 2017. PMID: 28758997 Free PMC article.
487 results