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PP2A methylation controls sensitivity and resistance to β-amyloid-induced cognitive and electrophysiological impairments.
Nicholls RE, Sontag JM, Zhang H, Staniszewski A, Yan S, Kim CY, Yim M, Woodruff CM, Arning E, Wasek B, Yin D, Bottiglieri T, Sontag E, Kandel ER, Arancio O. Nicholls RE, et al. Proc Natl Acad Sci U S A. 2016 Mar 22;113(12):3347-52. doi: 10.1073/pnas.1521018113. Epub 2016 Mar 7. Proc Natl Acad Sci U S A. 2016. PMID: 26951658 Free PMC article.
Reduced Expression of the PP2A Methylesterase, PME-1, or the PP2A Methyltransferase, LCMT-1, Alters Sensitivity to Beta-Amyloid-Induced Cognitive and Electrophysiological Impairments in Mice.
Staniszewski A, Zhang H, Asam K, Pitstick R, Kavanaugh MP, Arancio O, Nicholls RE. Staniszewski A, et al. Among authors: nicholls re. J Neurosci. 2020 Jun 3;40(23):4596-4608. doi: 10.1523/JNEUROSCI.2983-19.2020. Epub 2020 Apr 27. J Neurosci. 2020. PMID: 32341098 Free PMC article.
Eicosanoyl-5-hydroxytryptamide (EHT) prevents Alzheimer's disease-related cognitive and electrophysiological impairments in mice exposed to elevated concentrations of oligomeric beta-amyloid.
Asam K, Staniszewski A, Zhang H, Melideo SL, Mazzeo A, Voronkov M, Huber KL, Pérez E, Stock M, Stock JB, Arancio O, Nicholls RE. Asam K, et al. Among authors: nicholls re. PLoS One. 2017 Dec 18;12(12):e0189413. doi: 10.1371/journal.pone.0189413. eCollection 2017. PLoS One. 2017. PMID: 29253878 Free PMC article.
14 results