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Structural and functional characterization of a putative de novo gene in Drosophila.
Nat Commun. 2021 Mar 12;12(1):1667. doi: 10.1038/s41467-021-21667-6.
Nat Commun. 2021.
PMID: 33712569
Free PMC article.
Becoming a de novo gene.
Bornberg-Bauer E, Heames B.
Bornberg-Bauer E, et al. Among authors: heames b.
Nat Ecol Evol. 2019 Apr;3(4):524-525. doi: 10.1038/s41559-019-0845-y.
Nat Ecol Evol. 2019.
PMID: 30858587
No abstract available.
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A Continuum of Evolving De Novo Genes Drives Protein-Coding Novelty in Drosophila.
Heames B, Schmitz J, Bornberg-Bauer E.
Heames B, et al.
J Mol Evol. 2020 May;88(4):382-398. doi: 10.1007/s00239-020-09939-z. Epub 2020 Apr 7.
J Mol Evol. 2020.
PMID: 32253450
Free PMC article.
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Accessing unexplored regions of sequence space in directed enzyme evolution via insertion/deletion mutagenesis.
Emond S, Petek M, Kay EJ, Heames B, Devenish SRA, Tokuriki N, Hollfelder F.
Emond S, et al. Among authors: heames b.
Nat Commun. 2020 Jul 10;11(1):3469. doi: 10.1038/s41467-020-17061-3.
Nat Commun. 2020.
PMID: 32651386
Free PMC article.
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High-throughput Selection of Human de novo-emerged sORFs with High Folding Potential.
Aubel M, Buchel F, Heames B, Jones A, Honc O, Bornberg-Bauer E, Hlouchova K.
Aubel M, et al. Among authors: heames b.
Genome Biol Evol. 2024 Apr 2;16(4):evae069. doi: 10.1093/gbe/evae069.
Genome Biol Evol. 2024.
PMID: 38597156
Free PMC article.
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Experimental characterization of de novo proteins and their unevolved random-sequence counterparts.
Heames B, Buchel F, Aubel M, Tretyachenko V, Loginov D, Novák P, Lange A, Bornberg-Bauer E, Hlouchová K.
Heames B, et al.
Nat Ecol Evol. 2023 Apr;7(4):570-580. doi: 10.1038/s41559-023-02010-2. Epub 2023 Apr 6.
Nat Ecol Evol. 2023.
PMID: 37024625
Free PMC article.
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Dissecting how modular polyketide synthase ketoreductases interact with acyl carrier protein-attached substrates.
Moretto L, Vance S, Heames B, Broadhurst RW.
Moretto L, et al. Among authors: heames b.
Chem Commun (Camb). 2017 Oct 25;53(83):11457-11460. doi: 10.1039/c7cc04625a. Epub 2017 Oct 5.
Chem Commun (Camb). 2017.
PMID: 28980673
Free PMC article.
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