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Covalent Fragment Screening and Optimization Identifies the Chloroacetohydrazide Scaffold as Inhibitors for Ubiquitin C-terminal Hydrolase L1.
Imhoff RD, Patel R, Safdar MH, Jones HBL, Pinto-Fernandez A, Vendrell I, Chen H, Muli CS, Krabill AD, Kessler BM, Wendt MK, Das C, Flaherty DP. Imhoff RD, et al. Among authors: jones hbl. J Med Chem. 2024 Mar 28;67(6):4496-4524. doi: 10.1021/acs.jmedchem.3c01661. Epub 2024 Mar 15. J Med Chem. 2024. PMID: 38488146
Deubiquitinases in muscle physiology and disorders.
Olie CS, O'Brien DP, Jones HBL, Liang Z, Damianou A, Sur-Erdem I, Pinto-Fernández A, Raz V, Kessler BM. Olie CS, et al. Among authors: jones hbl. Biochem Soc Trans. 2024 May 8:BST20230562. doi: 10.1042/BST20230562. Online ahead of print. Biochem Soc Trans. 2024. PMID: 38716888
The impact of sequencing depth on the inferred taxonomic composition and AMR gene content of metagenomic samples.
Gweon HS, Shaw LP, Swann J, De Maio N, AbuOun M, Niehus R, Hubbard ATM, Bowes MJ, Bailey MJ, Peto TEA, Hoosdally SJ, Walker AS, Sebra RP, Crook DW, Anjum MF, Read DS, Stoesser N; REHAB consortium. Gweon HS, et al. Environ Microbiome. 2019 Oct 24;14(1):7. doi: 10.1186/s40793-019-0347-1. Environ Microbiome. 2019. PMID: 33902704 Free PMC article.
A genomic epidemiological study shows that prevalence of antimicrobial resistance in Enterobacterales is associated with the livestock host, as well as antimicrobial usage.
AbuOun M, Jones H, Stubberfield E, Gilson D, Shaw LP, Hubbard ATM, Chau KK, Sebra R, Peto TEA, Crook DW, Read DS, Gweon HS, Walker AS, Stoesser N, Smith RP, Anjum MF, On Behalf Of The Rehab Consortium. AbuOun M, et al. Microb Genom. 2021 Oct;7(10):000630. doi: 10.1099/mgen.0.000630. Microb Genom. 2021. PMID: 34609275 Free PMC article.
17 results