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Tumor suppressor mediated ubiquitylation of hnRNPK is a barrier to oncogenic translation.
Mucha B, Qie S, Bajpai S, Tarallo V, Diehl JN, Tedeschi F, Zhou G, Gao Z, Flashner S, Klein-Szanto AJ, Hibshoosh H, Masataka S, Chajewski OS, Majsterek I, Pytel D, Hatzoglou M, Der CJ, Nakagawa H, Bass AJ, Wong KK, Fuchs SY, Rustgi AK, Jankowsky E, Diehl JA. Mucha B, et al. Among authors: chajewski os. Nat Commun. 2022 Nov 3;13(1):6614. doi: 10.1038/s41467-022-34402-6. Nat Commun. 2022. PMID: 36329064 Free PMC article.
PERK Is a Haploinsufficient Tumor Suppressor: Gene Dose Determines Tumor-Suppressive Versus Tumor Promoting Properties of PERK in Melanoma.
Pytel D, Gao Y, Mackiewicz K, Katlinskaya YV, Staschke KA, Paredes MC, Yoshida A, Qie S, Zhang G, Chajewski OS, Wu L, Majsterek I, Herlyn M, Fuchs SY, Diehl JA. Pytel D, et al. Among authors: chajewski os. PLoS Genet. 2016 Dec 15;12(12):e1006518. doi: 10.1371/journal.pgen.1006518. eCollection 2016 Dec. PLoS Genet. 2016. PMID: 27977682 Free PMC article.