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Potent neutralizing nanobodies resist convergent circulating variants of SARS-CoV-2 by targeting novel and conserved epitopes.
Sun D, Sang Z, Kim YJ, Xiang Y, Cohen T, Belford AK, Huet A, Conway JF, Sun J, Taylor DJ, Schneidman-Duhovny D, Zhang C, Huang W, Shi Y. Sun D, et al. Among authors: shi y. bioRxiv [Preprint]. 2021 Mar 10:2021.03.09.434592. doi: 10.1101/2021.03.09.434592. bioRxiv. 2021. Update in: Nat Commun. 2021 Aug 3;12(1):4676. doi: 10.1038/s41467-021-24963-3. PMID: 33758850 Free PMC article. Updated. Preprint.
Versatile and multivalent nanobodies efficiently neutralize SARS-CoV-2.
Xiang Y, Nambulli S, Xiao Z, Liu H, Sang Z, Duprex WP, Schneidman-Duhovny D, Zhang C, Shi Y. Xiang Y, et al. Among authors: shi y. Science. 2020 Dec 18;370(6523):1479-1484. doi: 10.1126/science.abe4747. Epub 2020 Nov 5. Science. 2020. PMID: 33154108 Free PMC article.
Inhalable Nanobody (PiN-21) prevents and treats SARS-CoV-2 infections in Syrian hamsters at ultra-low doses.
Nambulli S, Xiang Y, Tilston-Lunel NL, Rennick LJ, Sang Z, Klimstra WB, Reed DS, Crossland NA, Shi Y, Duprex WP. Nambulli S, et al. Among authors: shi y. bioRxiv [Preprint]. 2021 Feb 23:2021.02.23.432569. doi: 10.1101/2021.02.23.432569. bioRxiv. 2021. Update in: Sci Adv. 2021 May 26;7(22):eabh0319. doi: 10.1126/sciadv.abh0319. PMID: 33655253 Free PMC article. Updated. Preprint.
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