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Sulforaphane exhibits in vitro and in vivo antiviral activity against pandemic SARS-CoV-2 and seasonal HCoV-OC43 coronaviruses.
Ordonez AA, Bullen CK, Villabona-Rueda AF, Thompson EA, Turner ML, Davis SL, Komm O, Powell JD, D'Alessio FR, Yolken RH, Jain SK, Jones-Brando L. Ordonez AA, et al. Among authors: thompson ea. bioRxiv [Preprint]. 2021 Mar 25:2021.03.25.437060. doi: 10.1101/2021.03.25.437060. bioRxiv. 2021. Update in: Commun Biol. 2022 Mar 18;5(1):242. doi: 10.1038/s42003-022-03189-z. PMID: 33791708 Free PMC article. Updated. Preprint.
Metabolic programs define dysfunctional immune responses in severe COVID-19 patients.
Thompson EA, Cascino K, Ordonez AA, Zhou W, Vaghasia A, Hamacher-Brady A, Brady NR, Sun IH, Wang R, Rosenberg AZ, Delannoy M, Rothman R, Fenstermacher K, Sauer L, Shaw-Saliba K, Bloch EM, Redd AD, Tobian AA, Horton M, Smith K, Pekosz A, D'Alessio FR, Yegnasubramanian S, Ji H, Cox AL, Powell JD. Thompson EA, et al. medRxiv [Preprint]. 2020 Oct 5:2020.09.10.20186064. doi: 10.1101/2020.09.10.20186064. medRxiv. 2020. Update in: Cell Rep. 2021 Mar 16;34(11):108863. doi: 10.1016/j.celrep.2021.108863. PMID: 32935120 Free PMC article. Updated. Preprint.
Metabolic programs define dysfunctional immune responses in severe COVID-19 patients.
Thompson EA, Cascino K, Ordonez AA, Zhou W, Vaghasia A, Hamacher-Brady A, Brady NR, Sun IH, Wang R, Rosenberg AZ, Delannoy M, Rothman R, Fenstermacher K, Sauer L, Shaw-Saliba K, Bloch EM, Redd AD, Tobian AAR, Horton M, Smith K, Pekosz A, D'Alessio FR, Yegnasubramanian S, Ji H, Cox AL, Powell JD. Thompson EA, et al. Cell Rep. 2021 Mar 16;34(11):108863. doi: 10.1016/j.celrep.2021.108863. Epub 2021 Feb 26. Cell Rep. 2021. PMID: 33691089 Free PMC article.
Functional characterization of CD4+ T cell receptors crossreactive for SARS-CoV-2 and endemic coronaviruses.
Dykema AG, Zhang B, Woldemeskel BA, Garliss CC, Cheung LS, Choudhury D, Zhang J, Aparicio L, Bom S, Rashid R, Caushi JX, Hsiue EH, Cascino K, Thompson EA, Kwaa AK, Singh D, Thapa S, Ordonez AA, Pekosz A, D'Alessio FR, Powell JD, Yegnasubramanian S, Zhou S, Pardoll DM, Ji H, Cox AL, Blankson JN, Smith KN. Dykema AG, et al. Among authors: thompson ea. J Clin Invest. 2021 May 17;131(10):e146922. doi: 10.1172/JCI146922. J Clin Invest. 2021. PMID: 33830946 Free PMC article.
Sulforaphane exhibits antiviral activity against pandemic SARS-CoV-2 and seasonal HCoV-OC43 coronaviruses in vitro and in mice.
Ordonez AA, Bullen CK, Villabona-Rueda AF, Thompson EA, Turner ML, Merino VF, Yan Y, Kim J, Davis SL, Komm O, Powell JD, D'Alessio FR, Yolken RH, Jain SK, Jones-Brando L. Ordonez AA, et al. Among authors: thompson ea. Commun Biol. 2022 Mar 18;5(1):242. doi: 10.1038/s42003-022-03189-z. Commun Biol. 2022. PMID: 35304580 Free PMC article.
Distinct Myeloid Derived Suppressor Cell Populations Promote Tumor Aggression in Glioblastoma.
Jackson C, Cherry C, Bom S, Dykema AG, Thompson E, Zheng M, Ji Z, Hou W, Li R, Zhang H, Choi J, Rodriguez F, Weingart J, Yegnasubramanian S, Lim M, Bettegowda C, Powell J, Eliesseff J, Ji H, Pardoll D. Jackson C, et al. bioRxiv [Preprint]. 2023 Mar 27:2023.03.26.534192. doi: 10.1101/2023.03.26.534192. bioRxiv. 2023. PMID: 37034584 Free PMC article. Preprint.
An exploratory study of metformin with or without rapamycin as maintenance therapy after induction chemotherapy in patients with metastatic pancreatic adenocarcinoma.
Bever KM, Borazanci EH, Thompson EA, Durham JN, Pinero K, Jameson GS, Vrana A, Liu M, Wilt C, Wu AA, Fu W, Wang H, Yin Y, Leal JP, Jesus-Acosta A, Zheng L, Laheru DA, Von Hoff DD, Jaffee EM, Powell JD, Le DT. Bever KM, et al. Among authors: thompson ea. Oncotarget. 2020 May 26;11(21):1929-1941. doi: 10.18632/oncotarget.27586. eCollection 2020 May 26. Oncotarget. 2020. PMID: 32523648 Free PMC article.
Metabolic reprogramming of tumor-associated macrophages using glutamine antagonist JHU083 drives tumor immunity in myeloid-rich prostate and bladder cancer tumors.
Praharaj M, Shen F, Lee AJ, Zhao L, Nirschl TR, Theodros D, Singh AK, Wang X, Adusei KM, Lombardo KA, Williams RA, Sena LA, Thompson EA, Tam A, Yegnasubramanian S, Pearce EJ, Leone RD, Alt J, Rais R, Slusher BS, Pardoll DM, Powell JD, Zarif JC. Praharaj M, et al. Among authors: thompson ea. Cancer Immunol Res. 2024 May 3. doi: 10.1158/2326-6066.CIR-23-1105. Online ahead of print. Cancer Immunol Res. 2024. PMID: 38701369
576 results