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A detailed view of 2-methylisoborneol biosynthesis.
Brock NL, Ravella SR, Schulz S, Dickschat JS. Brock NL, et al. Among authors: ravella sr. Angew Chem Int Ed Engl. 2013 Feb 11;52(7):2100-4. doi: 10.1002/anie.201209173. Epub 2013 Jan 11. Angew Chem Int Ed Engl. 2013. PMID: 23316002 No abstract available.
Usmarapride (SUVN-D4010), a 5-HT4 receptor partial agonist for the potential treatment of Alzheimer's disease: Behavioural, neurochemical and pharmacological profiling.
Nirogi R, Grandhi VR, Medapati R, Ganuga N, Abraham R, Thentu JB, Palacharla VRC, Petlu S, Srirangavaram M, Subramanian R, Ravella SR, Gagginapally SR, Benade V, Jayarajan P, Mohammed AR. Nirogi R, et al. Among authors: ravella sr. Eur J Pharmacol. 2023 May 15;947:175625. doi: 10.1016/j.ejphar.2023.175625. Epub 2023 Mar 28. Eur J Pharmacol. 2023. PMID: 36997046
Discovery and Preclinical Characterization of Usmarapride (SUVN-D4010): A Potent, Selective 5-HT4 Receptor Partial Agonist for the Treatment of Cognitive Deficits Associated with Alzheimer's Disease.
Nirogi R, Mohammed AR, Shinde AK, Gagginapally SR, Kancharla DM, Ravella SR, Bogaraju N, Middekadi VR, Subramanian R, Palacharla RC, Benade V, Muddana N, Abraham R, Medapati RB, Thentu JB, Mekala VR, Petlu S, Lingavarapu BB, Yarra S, Kagita N, Goyal VK, Pandey SK, Jasti V. Nirogi R, et al. Among authors: ravella sr. J Med Chem. 2021 Aug 12;64(15):10641-10665. doi: 10.1021/acs.jmedchem.1c00703. Epub 2021 Jul 12. J Med Chem. 2021. PMID: 34251799
Discovery and Development of 3-(6-Chloropyridine-3-yloxymethyl)-2-azabicyclo[3.1.0]hexane Hydrochloride (SUVN-911): A Novel, Potent, Selective, and Orally Active Neuronal Nicotinic Acetylcholine α4β2 Receptor Antagonist for the Treatment of Depression.
Nirogi R, Mohammed AR, Shinde AK, Ravella SR, Bogaraju N, Subramanian R, Mekala VR, Palacharla RC, Muddana N, Thentu JB, Bhyrapuneni G, Abraham R, Jasti V. Nirogi R, et al. Among authors: ravella sr. J Med Chem. 2020 Mar 26;63(6):2833-2853. doi: 10.1021/acs.jmedchem.9b00790. Epub 2020 Feb 21. J Med Chem. 2020. PMID: 32026697
Synthesis, Structure-Activity Relationships, and Preclinical Evaluation of Heteroaromatic Amides and 1,3,4-Oxadiazole Derivatives as 5-HT4 Receptor Partial Agonists.
Nirogi R, Mohammed AR, Shinde AK, Gagginapally SR, Kancharla DM, Middekadi VR, Bogaraju N, Ravella SR, Singh P, Birangal SR, Subramanian R, Palacharla RC, Benade V, Muddana N, Jayarajan P. Nirogi R, et al. Among authors: ravella sr. J Med Chem. 2018 Jun 14;61(11):4993-5008. doi: 10.1021/acs.jmedchem.8b00457. Epub 2018 May 31. J Med Chem. 2018. PMID: 29763304
18 results