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Rationale design of novel substituted 1,3,5-triazine candidates as dual IDH1(R132H)/ IDH2(R140Q) inhibitors with high selectivity against acute myeloid leukemia: In vitro and in vivo preclinical investigations.
Tawfik HO, Mousa MHA, Zaky MY, El-Dessouki AM, Sharaky M, Abdullah O, El-Hamamsy MH, Al-Karmalawy AA. Tawfik HO, et al. Among authors: mousa mha. Bioorg Chem. 2024 May 21;149:107483. doi: 10.1016/j.bioorg.2024.107483. Online ahead of print. Bioorg Chem. 2024. PMID: 38805913
378 results