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The push and pull of DNA methylation.
Gu T, Goodell MA. Gu T, et al. Among authors: goodell ma. Science. 2021 Apr 9;372(6538):128-129. doi: 10.1126/science.abh3187. Science. 2021. PMID: 33833110 No abstract available.
Stem cells and healthy aging.
Goodell MA, Rando TA. Goodell MA, et al. Science. 2015 Dec 4;350(6265):1199-204. doi: 10.1126/science.aab3388. Science. 2015. PMID: 26785478 Review.
Large DNA Methylation Nadirs Anchor Chromatin Loops Maintaining Hematopoietic Stem Cell Identity.
Zhang X, Jeong M, Huang X, Wang XQ, Wang X, Zhou W, Shamim MS, Gore H, Himadewi P, Liu Y, Bochkov ID, Reyes J, Doty M, Huang YH, Jung H, Heikamp E, Aiden AP, Li W, Su J, Aiden EL, Goodell MA. Zhang X, et al. Among authors: goodell ma. Mol Cell. 2020 May 7;78(3):506-521.e6. doi: 10.1016/j.molcel.2020.04.018. Mol Cell. 2020. PMID: 32386543 Free PMC article.
Constitutive loss of DNMT3A causes morbid obesity through misregulation of adipogenesis.
Tovy A, Reyes JM, Zhang L, Huang YH, Rosas C, Daquinag AC, Guzman A, Ramabadran R, Chen CW, Gu T, Gupta S, Ortinau L, Park D, Cox AR, Rau RE, Hartig SM, Kolonin MG, Goodell MA. Tovy A, et al. Among authors: goodell ma. Elife. 2022 May 30;11:e72359. doi: 10.7554/eLife.72359. Elife. 2022. PMID: 35635747 Free PMC article.
DNMT3A-coordinated splicing governs the stem state switch towards differentiation in embryonic and haematopoietic stem cells.
Ramabadran R, Wang JH, Reyes JM, Guzman AG, Gupta S, Rosas C, Brunetti L, Gundry MC, Tovy A, Long H, Gu T, Cullen SM, Tyagi S, Rux D, Kim JJ, Kornblau SM, Kyba M, Stossi F, Rau RE, Takahashi K, Westbrook TF, Goodell MA. Ramabadran R, et al. Among authors: goodell ma. Nat Cell Biol. 2023 Apr;25(4):528-539. doi: 10.1038/s41556-023-01109-9. Epub 2023 Apr 6. Nat Cell Biol. 2023. PMID: 37024683 Free PMC article.
196 results