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De novo purine biosynthesis is a major driver of chemoresistance in glioblastoma.
Shireman JM, Atashi F, Lee G, Ali ES, Saathoff MR, Park CH, Savchuk S, Baisiwala S, Miska J, Lesniak MS, James CD, Stupp R, Kumthekar P, Horbinski CM, Ben-Sahra I, Ahmed AU. Shireman JM, et al. Brain. 2021 May 7;144(4):1230-1246. doi: 10.1093/brain/awab020. Brain. 2021. PMID: 33855339 Free PMC article.
Activation of Dopamine Receptor 2 Prompts Transcriptomic and Metabolic Plasticity in Glioblastoma.
Caragher SP, Shireman JM, Huang M, Miska J, Atashi F, Baisiwala S, Hong Park C, Saathoff MR, Warnke L, Xiao T, Lesniak MS, James CD, Meltzer H, Tryba AK, Ahmed AU. Caragher SP, et al. Among authors: shireman jm. J Neurosci. 2019 Mar 13;39(11):1982-1993. doi: 10.1523/JNEUROSCI.1589-18.2018. Epub 2019 Jan 16. J Neurosci. 2019. PMID: 30651332 Free PMC article.
Ribonucleotide reductase regulatory subunit M2 drives glioblastoma TMZ resistance through modulation of dNTP production.
Perrault EN, Shireman JM, Ali ES, Lin P, Preddy I, Park C, Budhiraja S, Baisiwala S, Dixit K, James CD, Heiland DH, Ben-Sahra I, Pott S, Basu A, Miska J, Ahmed AU. Perrault EN, et al. Among authors: shireman jm. Sci Adv. 2023 May 19;9(20):eade7236. doi: 10.1126/sciadv.ade7236. Epub 2023 May 17. Sci Adv. 2023. PMID: 37196077 Free PMC article.
The CXCL16-CXCR6 axis in glioblastoma modulates T-cell activity in a spatiotemporal context.
Chia TY, Billingham LK, Boland L, Katz JL, Arrieta VA, Shireman J, Rosas AL, DeLay SL, Zillinger K, Geng Y, Kruger J, Silvers C, Wang H, Vazquez Cervantes GI, Hou D, Wang S, Wan H, Sonabend A, Zhang P, Lee-Chang C, Miska J. Chia TY, et al. Front Immunol. 2024 Jan 17;14:1331287. doi: 10.3389/fimmu.2023.1331287. eCollection 2023. Front Immunol. 2024. PMID: 38299146 Free PMC article.
21 results