Sandoval IM - Search Results

1

Netrin-1 receptor UNC5C cleavage by active δ-secretase enhances neurodegeneration, promoting Alzheimer's disease pathologies.

Chen G, Kang SS, Wang Z, Ahn EH, Xia Y, Liu X, Sandoval IM, Manfredsson FP, Zhang Z, Ye K. Chen G, et al. Among authors: sandoval im. Sci Adv. 2021 Apr 16;7(16):eabe4499. doi: 10.1126/sciadv.abe4499. Print 2021 Apr. Sci Adv. 2021. PMID: 33863723 Free PMC article.

2

Intrastriatal injection of pre-formed mouse α-synuclein fibrils into rats triggers α-synuclein pathology and bilateral nigrostriatal degeneration.

Paumier KL, Luk KC, Manfredsson FP, Kanaan NM, Lipton JW, Collier TJ, Steece-Collier K, Kemp CJ, Celano S, Schulz E, Sandoval IM, Fleming S, Dirr E, Polinski NK, Trojanowski JQ, Lee VM, Sortwell CE. Paumier KL, et al. Among authors: sandoval im. Neurobiol Dis. 2015 Oct;82:185-199. doi: 10.1016/j.nbd.2015.06.003. Epub 2015 Jun 17. Neurobiol Dis. 2015. PMID: 26093169 Free PMC article.

3

Continuous Collection of Adeno-Associated Virus from Producer Cell Medium Significantly Increases Total Viral Yield.

Benskey MJ, Sandoval IM, Manfredsson FP. Benskey MJ, et al. Among authors: sandoval im. Hum Gene Ther Methods. 2016 Feb;27(1):32-45. doi: 10.1089/hgtb.2015.117. Hum Gene Ther Methods. 2016. PMID: 26863210

4

Delta-Secretase Phosphorylation by SRPK2 Enhances Its Enzymatic Activity, Provoking Pathogenesis in Alzheimer's Disease.

Wang ZH, Liu P, Liu X, Manfredsson FP, Sandoval IM, Yu SP, Wang JZ, Ye K. Wang ZH, et al. Among authors: sandoval im. Mol Cell. 2017 Sep 7;67(5):812-825.e5. doi: 10.1016/j.molcel.2017.07.018. Epub 2017 Aug 17. Mol Cell. 2017. PMID: 28826672 Free PMC article.

5

Induction of alpha-synuclein pathology in the enteric nervous system of the rat and non-human primate results in gastrointestinal dysmotility and transient CNS pathology.

Manfredsson FP, Luk KC, Benskey MJ, Gezer A, Garcia J, Kuhn NC, Sandoval IM, Patterson JR, O'Mara A, Yonkers R, Kordower JH. Manfredsson FP, et al. Among authors: sandoval im. Neurobiol Dis. 2018 Apr;112:106-118. doi: 10.1016/j.nbd.2018.01.008. Epub 2018 Jan 16. Neurobiol Dis. 2018. PMID: 29341898 Free PMC article.

6

Silencing Alpha Synuclein in Mature Nigral Neurons Results in Rapid Neuroinflammation and Subsequent Toxicity.

Benskey MJ, Sellnow RC, Sandoval IM, Sortwell CE, Lipton JW, Manfredsson FP. Benskey MJ, et al. Among authors: sandoval im. Front Mol Neurosci. 2018 Feb 13;11:36. doi: 10.3389/fnmol.2018.00036. eCollection 2018. Front Mol Neurosci. 2018. PMID: 29497361 Free PMC article.

7

C/EBPβ regulates delta-secretase expression and mediates pathogenesis in mouse models of Alzheimer's disease.

Wang ZH, Gong K, Liu X, Zhang Z, Sun X, Wei ZZ, Yu SP, Manfredsson FP, Sandoval IM, Johnson PF, Jia J, Wang JZ, Ye K. Wang ZH, et al. Among authors: sandoval im. Nat Commun. 2018 May 3;9(1):1784. doi: 10.1038/s41467-018-04120-z. Nat Commun. 2018. PMID: 29725016 Free PMC article.

8

α-Synuclein stimulation of monoamine oxidase-B and legumain protease mediates the pathology of Parkinson's disease.

Kang SS, Ahn EH, Zhang Z, Liu X, Manfredsson FP, Sandoval IM, Dhakal S, Iuvone PM, Cao X, Ye K. Kang SS, et al. Among authors: sandoval im. EMBO J. 2018 Jun 15;37(12):e98878. doi: 10.15252/embj.201798878. Epub 2018 May 16. EMBO J. 2018. PMID: 29769405 Free PMC article.

9

BDNF inhibits neurodegenerative disease-associated asparaginyl endopeptidase activity via phosphorylation by AKT.

Wang ZH, Wu W, Kang SS, Liu X, Wu Z, Peng J, Yu SP, Manfredsson FP, Sandoval IM, Liu X, Wang JZ, Ye K. Wang ZH, et al. Among authors: sandoval im. JCI Insight. 2018 Aug 23;3(16):e99007. doi: 10.1172/jci.insight.99007. eCollection 2018 Aug 23. JCI Insight. 2018. PMID: 30135302 Free PMC article.

10

Basic Concepts in Viral Vector-Mediated Gene Therapy.

Benskey MJ, Sandoval IM, Miller K, Sellnow RL, Gezer A, Kuhn NC, Vashon R, Manfredsson FP. Benskey MJ, et al. Among authors: sandoval im. Methods Mol Biol. 2019;1937:3-26. doi: 10.1007/978-1-4939-9065-8_1. Methods Mol Biol. 2019. PMID: 30706387

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