Guzman ML - Search Results

1

Inhibiting autophagy targets human leukemic stem cells and hypoxic AML blasts by disrupting mitochondrial homeostasis.

Dykstra KM, Fay HRS, Massey AC, Yang N, Johnson M, Portwood S, Guzman ML, Wang ES. Dykstra KM, et al. Among authors: guzman ml. Blood Adv. 2021 Apr 27;5(8):2087-2100. doi: 10.1182/bloodadvances.2020002666. Blood Adv. 2021. PMID: 33877295 Free PMC article.

2

Expression of tumor-suppressor genes interferon regulatory factor 1 and death-associated protein kinase in primitive acute myelogenous leukemia cells.

Guzman ML, Upchurch D, Grimes B, Howard DS, Rizzieri DA, Luger SM, Phillips GL, Jordan CT. Guzman ML, et al. Blood. 2001 Apr 1;97(7):2177-9. doi: 10.1182/blood.v97.7.2177. Blood. 2001. PMID: 11264190 Free article.

3

Nuclear factor-kappaB is constitutively activated in primitive human acute myelogenous leukemia cells.

Guzman ML, Neering SJ, Upchurch D, Grimes B, Howard DS, Rizzieri DA, Luger SM, Jordan CT. Guzman ML, et al. Blood. 2001 Oct 15;98(8):2301-7. doi: 10.1182/blood.v98.8.2301. Blood. 2001. PMID: 11588023 Free article.

4

The sesquiterpene lactone parthenolide induces apoptosis of human acute myelogenous leukemia stem and progenitor cells.

Guzman ML, Rossi RM, Karnischky L, Li X, Peterson DR, Howard DS, Jordan CT. Guzman ML, et al. Blood. 2005 Jun 1;105(11):4163-9. doi: 10.1182/blood-2004-10-4135. Epub 2005 Feb 1. Blood. 2005. PMID: 15687234 Free PMC article.

5

Rapid and selective death of leukemia stem and progenitor cells induced by the compound 4-benzyl, 2-methyl, 1,2,4-thiadiazolidine, 3,5 dione (TDZD-8).

Guzman ML, Li X, Corbett CA, Rossi RM, Bushnell T, Liesveld JL, Hébert J, Young F, Jordan CT. Guzman ML, et al. Blood. 2007 Dec 15;110(13):4436-44. doi: 10.1182/blood-2007-05-088815. Epub 2007 Sep 4. Blood. 2007. PMID: 17785584 Free PMC article.

6

An orally bioavailable parthenolide analog selectively eradicates acute myelogenous leukemia stem and progenitor cells.

Guzman ML, Rossi RM, Neelakantan S, Li X, Corbett CA, Hassane DC, Becker MW, Bennett JM, Sullivan E, Lachowicz JL, Vaughan A, Sweeney CJ, Matthews W, Carroll M, Liesveld JL, Crooks PA, Jordan CT. Guzman ML, et al. Blood. 2007 Dec 15;110(13):4427-35. doi: 10.1182/blood-2007-05-090621. Epub 2007 Sep 5. Blood. 2007. PMID: 17804695 Free PMC article.

7

Discovery of agents that eradicate leukemia stem cells using an in silico screen of public gene expression data.

Hassane DC, Guzman ML, Corbett C, Li X, Abboud R, Young F, Liesveld JL, Carroll M, Jordan CT. Hassane DC, et al. Among authors: guzman ml. Blood. 2008 Jun 15;111(12):5654-62. doi: 10.1182/blood-2007-11-126003. Epub 2008 Feb 27. Blood. 2008. PMID: 18305216 Free PMC article.

8

Chemical genomic screening reveals synergism between parthenolide and inhibitors of the PI-3 kinase and mTOR pathways.

Hassane DC, Sen S, Minhajuddin M, Rossi RM, Corbett CA, Balys M, Wei L, Crooks PA, Guzman ML, Jordan CT. Hassane DC, et al. Among authors: guzman ml. Blood. 2010 Dec 23;116(26):5983-90. doi: 10.1182/blood-2010-04-278044. Epub 2010 Oct 1. Blood. 2010. PMID: 20889920 Free article.

9

Acute myelogenous leukemia stem cells: from Bench to Bedside.

Felipe Rico J, Hassane DC, Guzman ML. Felipe Rico J, et al. Among authors: guzman ml. Cancer Lett. 2013 Sep 10;338(1):4-9. doi: 10.1016/j.canlet.2012.05.034. Epub 2012 Jun 17. Cancer Lett. 2013. PMID: 22713929 Free PMC article. Review.

10

Selective activity of the histone deacetylase inhibitor AR-42 against leukemia stem cells: a novel potential strategy in acute myelogenous leukemia.

Guzman ML, Yang N, Sharma KK, Balys M, Corbett CA, Jordan CT, Becker MW, Steidl U, Abdel-Wahab O, Levine RL, Marcucci G, Roboz GJ, Hassane DC. Guzman ML, et al. Mol Cancer Ther. 2014 Aug;13(8):1979-90. doi: 10.1158/1535-7163.MCT-13-0963. Epub 2014 Jun 16. Mol Cancer Ther. 2014. PMID: 24934933 Free PMC article.

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