Hackel BJ - Search Results

1

Extended yeast surface display linkers enhance the enrichment of ligands in direct mammalian cell selections.

Lown PS, Cai JJ, Ritter SC, Otolski JJ, Wong R, Hackel BJ. Lown PS, et al. Among authors: hackel bj. Protein Eng Des Sel. 2021 Feb 15;34:gzab004. doi: 10.1093/protein/gzab004. Protein Eng Des Sel. 2021. PMID: 33880560 Free PMC article.

2

Effect of Bottlebrush Poloxamer Architecture on Binding to Liposomes.

Hassler JF, Crabtree A, Liberman L, Bates FS, Hackel BJ, Lodge TP. Hassler JF, et al. Among authors: hackel bj. Biomacromolecules. 2023 Jan 9;24(1):449-461. doi: 10.1021/acs.biomac.2c01274. Epub 2022 Dec 23. Biomacromolecules. 2023. PMID: 36563027

3

Discovery of Kinetic Trapping of Poloxamers inside Liposomes via Thermal Treatment.

Hassler JF, Lawson M, Arroyo EC, Bates FS, Hackel BJ, Lodge TP. Hassler JF, et al. Among authors: hackel bj. Langmuir. 2023 Oct 10;39(40):14263-14274. doi: 10.1021/acs.langmuir.3c01499. Epub 2023 Sep 27. Langmuir. 2023. PMID: 37755825

4

Epidermal growth factor receptor downregulation by small heterodimeric binding proteins.

Hackel BJ, Neil JR, White FM, Wittrup KD. Hackel BJ, et al. Protein Eng Des Sel. 2012 Feb;25(2):47-57. doi: 10.1093/protein/gzr056. Epub 2011 Dec 9. Protein Eng Des Sel. 2012. PMID: 22160867 Free PMC article.

5

Ligand engineering using yeast surface display.

Hackel BJ. Hackel BJ. Methods Mol Biol. 2014;1163:257-71. doi: 10.1007/978-1-4939-0799-1_20. Methods Mol Biol. 2014. PMID: 24841314

6

A 45-Amino-Acid Scaffold Mined from the PDB for High-Affinity Ligand Engineering.

Kruziki MA, Bhatnagar S, Woldring DR, Duong VT, Hackel BJ. Kruziki MA, et al. Among authors: hackel bj. Chem Biol. 2015 Jul 23;22(7):946-56. doi: 10.1016/j.chembiol.2015.06.012. Epub 2015 Jul 9. Chem Biol. 2015. PMID: 26165154 Free PMC article.

7

Geometry and expression enhance enrichment of functional yeast-displayed ligands via cell panning.

Stern LA, Schrack IA, Johnson SM, Deshpande A, Bennett NR, Harasymiw LA, Gardner MK, Hackel BJ. Stern LA, et al. Among authors: hackel bj. Biotechnol Bioeng. 2016 Nov;113(11):2328-41. doi: 10.1002/bit.26001. Epub 2016 Jun 30. Biotechnol Bioeng. 2016. PMID: 27144954 Free PMC article.

8

Titratable Avidity Reduction Enhances Affinity Discrimination in Mammalian Cellular Selections of Yeast-Displayed Ligands.

Stern LA, Csizmar CM, Woldring DR, Wagner CR, Hackel BJ. Stern LA, et al. Among authors: hackel bj. ACS Comb Sci. 2017 May 8;19(5):315-323. doi: 10.1021/acscombsci.6b00191. Epub 2017 Mar 31. ACS Comb Sci. 2017. PMID: 28322543 Free PMC article.

9

Multispecies activity screening of microcin J25 mutants yields antimicrobials with increased specificity toward pathogenic Salmonella species relative to human commensal Escherichia coli.

Ritter SC, Yang ML, Kaznessis YN, Hackel BJ. Ritter SC, et al. Among authors: hackel bj. Biotechnol Bioeng. 2018 Oct;115(10):2394-2404. doi: 10.1002/bit.26772. Epub 2018 Jul 20. Biotechnol Bioeng. 2018. PMID: 29940080 Free PMC article.

10

Engineering an EGFR-binding Gp2 domain for increased hydrophilicity.

Du F, Kruziki MA, Zudock EJ, Zhang Y, Lown PS, Hackel BJ. Du F, et al. Among authors: hackel bj. Biotechnol Bioeng. 2019 Mar;116(3):526-535. doi: 10.1002/bit.26893. Epub 2018 Dec 30. Biotechnol Bioeng. 2019. PMID: 30536855 Free PMC article.

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