O'Brien-Simpson NM - Search Results

1

Human glucose-dependent insulinotropic polypeptide (GIP) is an antimicrobial adjuvant re-sensitising multidrug-resistant Gram-negative bacteria.

Jaradat DMM, Al-Karablieh N, Zaarer BHM, Li W, Saleh KKY, Rasras AJ, Abu-Romman S, O'Brien-Simpson NM, Wade JD. Jaradat DMM, et al. Biol Chem. 2021 Jan 11;402(4):513-524. doi: 10.1515/hsz-2020-0351. Print 2021 Mar 26. Biol Chem. 2021. PMID: 33938181

2

Label-free macrophage phenotype classification using machine learning methods.

Hourani T, Perez-Gonzalez A, Khoshmanesh K, Luwor R, Achuthan AA, Baratchi S, O'Brien-Simpson NM, Al-Hourani A. Hourani T, et al. Among authors: o brien simpson nm. Sci Rep. 2023 Mar 30;13(1):5202. doi: 10.1038/s41598-023-32158-7. Sci Rep. 2023. PMID: 36997576 Free PMC article.

3

Proline-rich antimicrobial peptides: potential therapeutics against antibiotic-resistant bacteria.

Li W, Tailhades J, O'Brien-Simpson NM, Separovic F, Otvos L Jr, Hossain MA, Wade JD. Li W, et al. Amino Acids. 2014 Oct;46(10):2287-94. doi: 10.1007/s00726-014-1820-1. Epub 2014 Aug 21. Amino Acids. 2014. PMID: 25141976 Review.

4

Multimerization of a Proline-Rich Antimicrobial Peptide, Chex-Arg20, Alters Its Mechanism of Interaction with the Escherichia coli Membrane.

Li W, O'Brien-Simpson NM, Tailhades J, Pantarat N, Dawson RM, Otvos L Jr, Reynolds EC, Separovic F, Hossain MA, Wade JD. Li W, et al. Chem Biol. 2015 Sep 17;22(9):1250-8. doi: 10.1016/j.chembiol.2015.08.011. Chem Biol. 2015. PMID: 26384569

5

A Rapid and Quantitative Flow Cytometry Method for the Analysis of Membrane Disruptive Antimicrobial Activity.

O'Brien-Simpson NM, Pantarat N, Attard TJ, Walsh KA, Reynolds EC. O'Brien-Simpson NM, et al. PLoS One. 2016 Mar 17;11(3):e0151694. doi: 10.1371/journal.pone.0151694. eCollection 2016. PLoS One. 2016. PMID: 26986223 Free PMC article.

6

Combating multidrug-resistant Gram-negative bacteria with structurally nanoengineered antimicrobial peptide polymers.

Lam SJ, O'Brien-Simpson NM, Pantarat N, Sulistio A, Wong EH, Chen YY, Lenzo JC, Holden JA, Blencowe A, Reynolds EC, Qiao GG. Lam SJ, et al. Nat Microbiol. 2016 Sep 12;1(11):16162. doi: 10.1038/nmicrobiol.2016.162. Nat Microbiol. 2016. PMID: 27617798

7

C-Terminal Modification and Multimerization Increase the Efficacy of a Proline-Rich Antimicrobial Peptide.

Li W, O'Brien-Simpson NM, Yao S, Tailhades J, Reynolds EC, Dawson RM, Otvos L Jr, Hossain MA, Separovic F, Wade JD. Li W, et al. Chemistry. 2017 Jan 5;23(2):390-396. doi: 10.1002/chem.201604172. Epub 2016 Nov 16. Chemistry. 2017. PMID: 27862429

8

Bionano Interaction Study on Antimicrobial Star-Shaped Peptide Polymer Nanoparticles.

Lam SJ, Wong EH, O'Brien-Simpson NM, Pantarat N, Blencowe A, Reynolds EC, Qiao GG. Lam SJ, et al. ACS Appl Mater Interfaces. 2016 Dec 14;8(49):33446-33456. doi: 10.1021/acsami.6b11402. Epub 2016 Nov 29. ACS Appl Mater Interfaces. 2016. PMID: 27960388

9

The Effect of Selective D- or N^α-Methyl Arginine Substitution on the Activity of the Proline-Rich Antimicrobial Peptide, Chex1-Arg20.

Li W, Sun Z, O'Brien-Simpson NM, Otvos L, Reynolds EC, Hossain MA, Separovic F, Wade JD. Li W, et al. Front Chem. 2017 Jan 19;5:1. doi: 10.3389/fchem.2017.00001. eCollection 2017. Front Chem. 2017. PMID: 28154813 Free PMC article.

10

Editorial: Antimicrobial and Anticancer Peptides.

O'Brien-Simpson NM, Hoffmann R, Chia CSB, Wade JD. O'Brien-Simpson NM, et al. Front Chem. 2018 Feb 6;6:13. doi: 10.3389/fchem.2018.00013. eCollection 2018. Front Chem. 2018. PMID: 29468150 Free PMC article. No abstract available.

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