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Integration of temporal single cell cellular stress response activity with logic-ODE modeling reveals activation of ATF4-CHOP axis as a critical predictor of drug-induced liver injury.
Wijaya LS, Trairatphisan P, Gabor A, Niemeijer M, Keet J, Alcalà Morera A, Snijders KE, Wink S, Yang H, Schildknecht S, Stevens JL, Bouwman P, Kamp H, Hengstler J, Beltman J, Leist M, Le Dévédec S, Saez-Rodriguez J, van de Water B. Wijaya LS, et al. Among authors: van de water b. Biochem Pharmacol. 2021 Aug;190:114591. doi: 10.1016/j.bcp.2021.114591. Epub 2021 May 4. Biochem Pharmacol. 2021. PMID: 33957093 Free article.
Cleavage of the actin-capping protein alpha -adducin at Asp-Asp-Ser-Asp633-Ala by caspase-3 is preceded by its phosphorylation on serine 726 in cisplatin-induced apoptosis of renal epithelial cells.
van de Water B, Tijdens IB, Verbrugge A, Huigsloot M, Dihal AA, Stevens JL, Jaken S, Mulder GJ. van de Water B, et al. J Biol Chem. 2000 Aug 18;275(33):25805-13. doi: 10.1074/jbc.M001680200. J Biol Chem. 2000. PMID: 10823823 Free article.
Decreased phosphorylation of focal adhesion kinase and paxillin is associated with loss of focal adhesions and stress fibers and precedes the onset of apoptosis (van de Water, B., Nagelkerke, J. F., and Stevens, J. L. (1999) J. ...
Decreased phosphorylation of focal adhesion kinase and paxillin is associated with loss of focal adhesions and stress fibers and precedes th …
Cellular stress responses and molecular mechanisms of nephrotoxicity.
van de Water B, de Graauw M, Le Dévédec S, Alderliesten M. van de Water B, et al. Among authors: de graauw m. Toxicol Lett. 2006 Mar 15;162(1):83-93. doi: 10.1016/j.toxlet.2005.10.014. Epub 2005 Dec 15. Toxicol Lett. 2006. PMID: 16359832 Review.
253 results