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Reply to Cheng et al.: COVID-19 induces lower extent of cytokines, but damages vascular endothelium by IL-6 signaling.
Kang S, Tanaka T, Inoue H, Ono C, Hashimoto S, Kioi Y, Matsumoto H, Matsuura H, Matsubara T, Shimizu K, Ogura H, Matsuura Y, Kishimoto T. Kang S, et al. Among authors: tanaka t. Proc Natl Acad Sci U S A. 2021 May 25;118(21):e2105040118. doi: 10.1073/pnas.2105040118. Proc Natl Acad Sci U S A. 2021. PMID: 33972413 Free PMC article. No abstract available.
IL-6 trans-signaling induces plasminogen activator inhibitor-1 from vascular endothelial cells in cytokine release syndrome.
Kang S, Tanaka T, Inoue H, Ono C, Hashimoto S, Kioi Y, Matsumoto H, Matsuura H, Matsubara T, Shimizu K, Ogura H, Matsuura Y, Kishimoto T. Kang S, et al. Among authors: tanaka t. Proc Natl Acad Sci U S A. 2020 Sep 8;117(36):22351-22356. doi: 10.1073/pnas.2010229117. Epub 2020 Aug 21. Proc Natl Acad Sci U S A. 2020. PMID: 32826331 Free PMC article.
IL-6 in inflammation, immunity, and disease.
Tanaka T, Narazaki M, Kishimoto T. Tanaka T, et al. Cold Spring Harb Perspect Biol. 2014 Sep 4;6(10):a016295. doi: 10.1101/cshperspect.a016295. Cold Spring Harb Perspect Biol. 2014. PMID: 25190079 Free PMC article. Review.
The role and therapeutic targeting of IL-6 in rheumatoid arthritis.
Narazaki M, Tanaka T, Kishimoto T. Narazaki M, et al. Among authors: tanaka t. Expert Rev Clin Immunol. 2017 Jun;13(6):535-551. doi: 10.1080/1744666X.2017.1295850. Epub 2017 Mar 3. Expert Rev Clin Immunol. 2017. PMID: 28494214 Review.
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