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Nuclear lamina integrity is required for proper spatial organization of chromatin in Drosophila.
Ulianov SV, Doronin SA, Khrameeva EE, Kos PI, Luzhin AV, Starikov SS, Galitsyna AA, Nenasheva VV, Ilyin AA, Flyamer IM, Mikhaleva EA, Logacheva MD, Gelfand MS, Chertovich AV, Gavrilov AA, Razin SV, Shevelyov YY. Ulianov SV, et al. Among authors: flyamer im. Nat Commun. 2019 Mar 12;10(1):1176. doi: 10.1038/s41467-019-09185-y. Nat Commun. 2019. PMID: 30862957 Free PMC article.
Developmentally regulated Shh expression is robust to TAD perturbations.
Williamson I, Kane L, Devenney PS, Flyamer IM, Anderson E, Kilanowski F, Hill RE, Bickmore WA, Lettice LA. Williamson I, et al. Among authors: flyamer im. Development. 2019 Sep 30;146(19):dev179523. doi: 10.1242/dev.179523. Development. 2019. PMID: 31511252 Free PMC article.
Coolpup.py: versatile pile-up analysis of Hi-C data.
Flyamer IM, Illingworth RS, Bickmore WA. Flyamer IM, et al. Bioinformatics. 2020 May 1;36(10):2980-2985. doi: 10.1093/bioinformatics/btaa073. Bioinformatics. 2020. PMID: 32003791 Free PMC article.
A central role for canonical PRC1 in shaping the 3D nuclear landscape.
Boyle S, Flyamer IM, Williamson I, Sengupta D, Bickmore WA, Illingworth RS. Boyle S, et al. Among authors: flyamer im. Genes Dev. 2020 Jul 1;34(13-14):931-949. doi: 10.1101/gad.336487.120. Epub 2020 May 21. Genes Dev. 2020. PMID: 32439634 Free PMC article.
Cohesin is required for long-range enhancer action at the Shh locus.
Kane L, Williamson I, Flyamer IM, Kumar Y, Hill RE, Lettice LA, Bickmore WA. Kane L, et al. Among authors: flyamer im. Nat Struct Mol Biol. 2022 Sep;29(9):891-897. doi: 10.1038/s41594-022-00821-8. Epub 2022 Sep 12. Nat Struct Mol Biol. 2022. PMID: 36097291 Free PMC article.
28 results