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A first-in-class, first-in-human, phase I trial of CIGB-552, a synthetic peptide targeting COMMD1 to inhibit the oncogenic activity of NF-κB in patients with advanced solid tumors.
Vallespi MG, Mestre B, Marrero MA, Uranga R, Rey D, Lugiollo M, Betancourt M, Silva K, Corrales D, Lamadrid Y, Rodriguez Y, Maceo A, Chaviano PP, Lemos G, Cabrales A, Freyre FM, Santana H, Garay HE, Oliva B, Fernandez JR. Vallespi MG, et al. Among authors: cabrales a. Int J Cancer. 2021 Sep 15;149(6):1313-1321. doi: 10.1002/ijc.33695. Epub 2021 May 27. Int J Cancer. 2021. PMID: 34019700 Free article. Clinical Trial.
Introducing an Asp-Pro linker in the synthesis of random one-bead-one-compound hexapeptide libraries compatible with ESI-MS analysis.
Masforrol Y, Gil J, González LJ, Pérez-Riverol Y, Fernández-de-Cossío J, Sánchez A, Betancourt LH, Garay HE, Cabrales A, Albericio F, Yang H, Zubarev RA, Besada V, Acosta OR. Masforrol Y, et al. Among authors: cabrales a. ACS Comb Sci. 2012 Mar 12;14(3):145-9. doi: 10.1021/co200159r. Epub 2012 Feb 28. ACS Comb Sci. 2012. PMID: 22280455
High efficacy of a 20 amino acid peptide of the acidic ribosomal protein P0 against the cattle tick, Rhipicephalus microplus.
Rodríguez-Mallon A, Encinosa PE, Méndez-Pérez L, Bello Y, Rodríguez Fernández R, Garay H, Cabrales A, Méndez L, Borroto C, Estrada MP. Rodríguez-Mallon A, et al. Among authors: cabrales a. Ticks Tick Borne Dis. 2015 Jun;6(4):530-7. doi: 10.1016/j.ttbdis.2015.04.007. Epub 2015 Apr 28. Ticks Tick Borne Dis. 2015. PMID: 25958782
Monoclonal antibody against Nile tilapia (Oreochromis niloticus) IgM heavy chain: A valuable tool for detection and quantification of IgM and IgM+ cells.
Velázquez J, Rodríguez A, Aragón H, Haidar A, González M, Valdés R, Garay HE, Abreu DD, Ramos Y, Cabrales A, Morales A, González O, Herrera F, Estrada MP, Carpio Y. Velázquez J, et al. Among authors: cabrales a. Fish Shellfish Immunol. 2021 Mar;110:44-54. doi: 10.1016/j.fsi.2020.12.007. Epub 2020 Dec 24. Fish Shellfish Immunol. 2021. PMID: 33348037
A recombinant SARS-CoV-2 receptor-binding domain expressed in an engineered fungal strain of Thermothelomyces heterothallica induces a functional immune response in mice.
Lazo L, Bequet-Romero M, Lemos G, Musacchio A, Cabrales A, Bruno AJ, Ariel Espinosa L, Saloheimo M, Vitikainen M, Hernández A, Emalfarb M, Tchelet R, Suzarte E, Guillén G. Lazo L, et al. Among authors: cabrales a. Vaccine. 2022 Feb 16;40(8):1162-1169. doi: 10.1016/j.vaccine.2022.01.007. Epub 2022 Jan 19. Vaccine. 2022. PMID: 35078661 Free PMC article.
Chimeric Antigen by the Fusion of SARS-CoV-2 Receptor Binding Domain with the Extracellular Domain of Human CD154: A Promising Improved Vaccine Candidate.
Ávalos I, Lao T, Rodríguez EM, Zamora Y, Rodríguez A, Ramón A, Lemos G, Cabrales A, Bequet-Romero M, Casillas D, Andújar I, Espinosa LA, González LJ, Alvarez Y, Carpio Y, Estrada MP. Ávalos I, et al. Among authors: cabrales a. Vaccines (Basel). 2022 Jun 3;10(6):897. doi: 10.3390/vaccines10060897. Vaccines (Basel). 2022. PMID: 35746505 Free PMC article.
Functional and Mass Spectrometric Evaluation of an Anti-Tick Antigen Based on the P0 Peptide Conjugated to Bm86 Protein.
Rodríguez Mallón A, Javier González L, Encinosa Guzmán PE, Bechara GH, Sanches GS, Pousa S, Cabrera G, Cabrales A, Garay H, Mejías R, López Álvarez JR, Bello Soto Y, Almeida F, Guirola O, Rodríguez Fernández R, Fuentes Castillo A, Méndez L, Jiménez S, Licea-Navarro A, Portela M, Durán R, Estrada MP. Rodríguez Mallón A, et al. Among authors: cabrales a. Pathogens. 2020 Jun 25;9(6):513. doi: 10.3390/pathogens9060513. Pathogens. 2020. PMID: 32630414 Free PMC article.
37 results