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Protective T cell receptor identification for orthotopic reprogramming of immunity in refractory virus infections.
Stief TA, Kaeuferle T, Müller TR, Döring M, Jablonowski LM, Schober K, Feucht J, Dennehy KM, Willier S, Blaeschke F, Handgretinger R, Lang P, Busch DH, Feuchtinger T. Stief TA, et al. Among authors: busch dh. Mol Ther. 2022 Jan 5;30(1):198-208. doi: 10.1016/j.ymthe.2021.05.021. Epub 2021 May 29. Mol Ther. 2022. PMID: 34058386 Free PMC article.
MHC multimer-guided and cell culture-independent isolation of functional T cell receptors from single cells facilitates TCR identification for immunotherapy.
Dössinger G, Bunse M, Bet J, Albrecht J, Paszkiewicz PJ, Weißbrich B, Schiedewitz I, Henkel L, Schiemann M, Neuenhahn M, Uckert W, Busch DH. Dössinger G, et al. Among authors: busch dh. PLoS One. 2013 Apr 26;8(4):e61384. doi: 10.1371/journal.pone.0061384. Print 2013. PLoS One. 2013. PMID: 23637823 Free PMC article.
TCR-ligand koff rate correlates with the protective capacity of antigen-specific CD8+ T cells for adoptive transfer.
Nauerth M, Weißbrich B, Knall R, Franz T, Dössinger G, Bet J, Paszkiewicz PJ, Pfeifer L, Bunse M, Uckert W, Holtappels R, Gillert-Marien D, Neuenhahn M, Krackhardt A, Reddehase MJ, Riddell SR, Busch DH. Nauerth M, et al. Among authors: busch dh. Sci Transl Med. 2013 Jul 3;5(192):192ra87. doi: 10.1126/scitranslmed.3005958. Sci Transl Med. 2013. PMID: 23825303 Free PMC article.
Lowest numbers of primary CD8(+) T cells can reconstitute protective immunity upon adoptive immunotherapy.
Stemberger C, Graef P, Odendahl M, Albrecht J, Dössinger G, Anderl F, Buchholz VR, Gasteiger G, Schiemann M, Grigoleit GU, Schuster FR, Borkhardt A, Versluys B, Tonn T, Seifried E, Einsele H, Germeroth L, Busch DH, Neuenhahn M. Stemberger C, et al. Among authors: busch dh. Blood. 2014 Jul 24;124(4):628-37. doi: 10.1182/blood-2013-12-547349. Epub 2014 May 22. Blood. 2014. PMID: 24855206 Free article.
T cell-specific inactivation of mouse CD2 by CRISPR/Cas9.
Beil-Wagner J, Dössinger G, Schober K, vom Berg J, Tresch A, Grandl M, Palle P, Mair F, Gerhard M, Becher B, Busch DH, Buch T. Beil-Wagner J, et al. Among authors: busch dh. Sci Rep. 2016 Feb 23;6:21377. doi: 10.1038/srep21377. Sci Rep. 2016. PMID: 26903281 Free PMC article.
Human HLA-A*02:01/CHM1+ allo-restricted T cell receptor transgenic CD8+ T cells specifically inhibit Ewing sarcoma growth in vitro and in vivo.
Blaeschke F, Thiel U, Kirschner A, Thiede M, Rubio RA, Schirmer D, Kirchner T, Richter GHS, Mall S, Klar R, Riddell S, Busch DH, Krackhardt A, Grunewald TG, Burdach S. Blaeschke F, et al. Among authors: busch dh. Oncotarget. 2016 Jul 12;7(28):43267-43280. doi: 10.18632/oncotarget.9218. Oncotarget. 2016. PMID: 27281613 Free PMC article.
364 results