Lee CA - Search Results

1

In Vitro Assessment of the Drug-Drug Interaction Potential of Verinurad and Its Metabolites as Substrates and Inhibitors of Metabolizing Enzymes and Drug Transporters.

Gopaul VS, Vildhede A, Andersson TB, Erlandsson F, Lee CA, Johansson S, Hilgendorf C. Gopaul VS, et al. Among authors: lee ca. J Pharmacol Exp Ther. 2021 Aug;378(2):108-123. doi: 10.1124/jpet.121.000549. Epub 2021 Jun 1. J Pharmacol Exp Ther. 2021. PMID: 34074714

2

ITC commentary on the prediction of digoxin clinical drug-drug interactions from in vitro transporter assays.

Lee CA, Kalvass JC, Galetin A, Zamek-Gliszczynski MJ. Lee CA, et al. Clin Pharmacol Ther. 2014 Sep;96(3):298-301. doi: 10.1038/clpt.2014.94. Clin Pharmacol Ther. 2014. PMID: 25141954

3

Intestinal P-gp and Putative Hepatic OATP1B Induction: International Transporter Consortium Perspective on Drug Development Implications.

Zamek-Gliszczynski MJ, Patel M, Yang X, Lutz JD, Chu X, Brouwer KLR, Lai Y, Lee CA, Neuhoff S, Paine MF, Sugiyama Y, Taskar KS, Galetin A. Zamek-Gliszczynski MJ, et al. Among authors: lee ca. Clin Pharmacol Ther. 2021 Jan;109(1):55-64. doi: 10.1002/cpt.1916. Epub 2020 Jul 9. Clin Pharmacol Ther. 2021. PMID: 32460379 Free PMC article. Review.

4

Drug-drug interactions mediated through P-glycoprotein: clinical relevance and in vitro-in vivo correlation using digoxin as a probe drug.

Fenner KS, Troutman MD, Kempshall S, Cook JA, Ware JA, Smith DA, Lee CA. Fenner KS, et al. Among authors: lee ca. Clin Pharmacol Ther. 2009 Feb;85(2):173-81. doi: 10.1038/clpt.2008.195. Epub 2008 Nov 5. Clin Pharmacol Ther. 2009. PMID: 18987624

5

In vitro characterization of axitinib interactions with human efflux and hepatic uptake transporters: implications for disposition and drug interactions.

Reyner EL, Sevidal S, West MA, Clouser-Roche A, Freiwald S, Fenner K, Ullah M, Lee CA, Smith BJ. Reyner EL, et al. Among authors: lee ca. Drug Metab Dispos. 2013 Aug;41(8):1575-83. doi: 10.1124/dmd.113.051193. Epub 2013 May 31. Drug Metab Dispos. 2013. PMID: 23729661

6

ITC Commentary on Metformin Clinical Drug-Drug Interaction Study Design That Enables an Efficacy- and Safety-Based Dose Adjustment Decision.

Zamek-Gliszczynski MJ, Chu X, Cook JA, Custodio JM, Galetin A, Giacomini KM, Lee CA, Paine MF, Ray AS, Ware JA, Wittwer MB, Zhang L; International Transporter Consortium. Zamek-Gliszczynski MJ, et al. Among authors: lee ca. Clin Pharmacol Ther. 2018 Nov;104(5):781-784. doi: 10.1002/cpt.1082. Epub 2018 May 15. Clin Pharmacol Ther. 2018. PMID: 29761830

7

P-glycoprotein related drug interactions: clinical importance and a consideration of disease states.

Lee CA, Cook JA, Reyner EL, Smith DA. Lee CA, et al. Expert Opin Drug Metab Toxicol. 2010 May;6(5):603-19. doi: 10.1517/17425251003610640. Expert Opin Drug Metab Toxicol. 2010. PMID: 20397967 Review.

8

Abundance of Drug Transporters in the Human Kidney Cortex as Quantified by Quantitative Targeted Proteomics.

Prasad B, Johnson K, Billington S, Lee C, Chung GW, Brown CD, Kelly EJ, Himmelfarb J, Unadkat JD. Prasad B, et al. Drug Metab Dispos. 2016 Dec;44(12):1920-1924. doi: 10.1124/dmd.116.072066. Epub 2016 Sep 12. Drug Metab Dispos. 2016. PMID: 27621205 Free PMC article.

9

Derivation of a System-Independent K_i for P-glycoprotein Mediated Digoxin Transport from System-Dependent IC₅₀ Data.

Chaudhry A, Chung G, Lynn A, Yalvigi A, Brown C, Ellens H, O'Connor M, Lee C, Bentz J. Chaudhry A, et al. Drug Metab Dispos. 2018 Mar;46(3):279-290. doi: 10.1124/dmd.117.075606. Epub 2018 Jan 9. Drug Metab Dispos. 2018. PMID: 29317410

10

Breast cancer resistance protein (ABCG2) in clinical pharmacokinetics and drug interactions: practical recommendations for clinical victim and perpetrator drug-drug interaction study design.

Lee CA, O'Connor MA, Ritchie TK, Galetin A, Cook JA, Ragueneau-Majlessi I, Ellens H, Feng B, Taub ME, Paine MF, Polli JW, Ware JA, Zamek-Gliszczynski MJ. Lee CA, et al. Drug Metab Dispos. 2015 Apr;43(4):490-509. doi: 10.1124/dmd.114.062174. Epub 2015 Jan 13. Drug Metab Dispos. 2015. PMID: 25587128 Review.

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