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Replication/Assembly Defective Avian Flavivirus With Internal Deletions in the Capsid Can Be Used as an Approach for Living Attenuated Vaccine.
He Y, Wang X, Guo J, Mao L, Zhang S, Hu T, Wang M, Jia R, Zhu D, Liu M, Zhao X, Yang Q, Wu Y, Zhang S, Huang J, Mao S, Ou X, Gao Q, Sun D, Liu Y, Zhang L, Yu Y, Cheng A, Chen S. He Y, et al. Among authors: guo j. Front Immunol. 2021 Aug 4;12:694959. doi: 10.3389/fimmu.2021.694959. eCollection 2021. Front Immunol. 2021. PMID: 34421904 Free PMC article.
N130, N175 and N207 are N-linked glycosylation sites of duck Tembusu virus NS1 that are important for viral multiplication, viremia and virulence in ducklings.
Zhang S, Wang X, He Y, Hu T, Guo J, Wang M, Jia R, Zhu D, Liu M, Zhao X, Yang Q, Wu Y, Zhang S, Huang J, Mao S, Ou X, Gao Q, Sun D, Liu Y, Zhang L, Chen S, Cheng A. Zhang S, et al. Among authors: guo j. Vet Microbiol. 2021 Oct;261:109215. doi: 10.1016/j.vetmic.2021.109215. Epub 2021 Aug 25. Vet Microbiol. 2021. PMID: 34455356
Stem-Loop I of the Tembusu Virus 3'-Untranslated Region Is Responsible for Viral Host-Specific Adaptation and the Pathogenicity of the Virus in Mice.
Mao L, He Y, Wu Z, Wang X, Guo J, Zhang S, Wang M, Jia R, Zhu D, Liu M, Zhao X, Yang Q, Mao S, Wu Y, Zhang S, Huang J, Ou X, Gao Q, Sun D, Cheng A, Chen S. Mao L, et al. Among authors: guo j. Microbiol Spectr. 2022 Oct 26;10(5):e0244922. doi: 10.1128/spectrum.02449-22. Epub 2022 Oct 10. Microbiol Spectr. 2022. PMID: 36214697 Free PMC article.
Attenuation of Avian Flavivirus by Rewiring the Leucine and Serine Codons of Its E-NS1 Protein toward Stop Mutation To Redirect Virus Evolution.
Guo J, He Y, Wang X, Merits A, Wang M, Jia R, Zhu D, Liu M, Zhao X, Yang Q, Wu Y, Zhang S, Huang J, Mao S, Ou X, Gao Q, Sun D, Tian B, Cheng A, Chen S. Guo J, et al. Microbiol Spectr. 2023 Feb 14;11(1):e0292122. doi: 10.1128/spectrum.02921-22. Epub 2023 Jan 10. Microbiol Spectr. 2023. PMID: 36625643 Free PMC article.
Comparative study of the pathogenicity of the mosquito origin strain and duck origin strain of Tembusu virus in ducklings and three-week-old mice.
Wang X, He Y, Guo J, Wu Z, Merits A, Wang M, Jia R, Zhu D, Liu M, Zhao X, Yang Q, Wu Y, Zhang S, Huang J, Ou X, Gao Q, Sun D, Cheng A, Chen S. Wang X, et al. Among authors: guo j. Virol Sin. 2023 Oct;38(5):827-831. doi: 10.1016/j.virs.2023.07.006. Epub 2023 Aug 5. Virol Sin. 2023. PMID: 37544649 Free PMC article.
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