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Page 1
N-glycolylneuraminic acid knockout reduces erythrocyte sequestration and thromboxane elaboration in an ex vivo pig-to-human xenoperfusion model.
Cimeno A, Hassanein W, French BM, Powell JM, Burdorf L, Goloubeva O, Cheng X, Parsell DM, Ramsoondar J, Kuravi K, Vaught T, Uluer MC, Redding E, O'Neill N, Laird C, Hershfeld A, Tatarov I, Thomas K, Ayares D, Azimzadeh AM, Pierson RN 3rd, Barth RN, LaMattina JC. Cimeno A, et al. Among authors: kuravi k. Xenotransplantation. 2017 Nov;24(6):10.1111/xen.12339. doi: 10.1111/xen.12339. Epub 2017 Sep 22. Xenotransplantation. 2017. PMID: 28940313 Free PMC article.
Allergic response to medical products in patients with alpha-gal syndrome.
Kuravi KV, Sorrells LT, Nellis JR, Rahman F, Walters AH, Matheny RG, Choudhary SK, Ayares DL, Commins SP, Bianchi JR, Turek JW. Kuravi KV, et al. J Thorac Cardiovasc Surg. 2022 Dec;164(6):e411-e424. doi: 10.1016/j.jtcvs.2021.03.100. Epub 2021 Apr 9. J Thorac Cardiovasc Surg. 2022. PMID: 33933257 Free PMC article.
Humanized von Willebrand factor reduces platelet sequestration in ex vivo and in vivo xenotransplant models.
Connolly MR, Kuravi K, Burdorf L, Sorrells L, Morrill B, Cimeno A, Vaught T, Dandro A, Sendil S, Habibabady ZA, Monahan J, Li T, LaMattina J, Eyestone W, Ayares D, Phelps C, Azimzadeh AM, Pierson RN 3rd. Connolly MR, et al. Among authors: kuravi k. Xenotransplantation. 2021 Nov;28(6):e12712. doi: 10.1111/xen.12712. Epub 2021 Oct 17. Xenotransplantation. 2021. PMID: 34657336 Free PMC article.
First clinical-grade porcine kidney xenotransplant using a human decedent model.
Porrett PM, Orandi BJ, Kumar V, Houp J, Anderson D, Cozette Killian A, Hauptfeld-Dolejsek V, Martin DE, Macedon S, Budd N, Stegner KL, Dandro A, Kokkinaki M, Kuravi KV, Reed RD, Fatima H, Killian JT Jr, Baker G, Perry J, Wright ED, Cheung MD, Erman EN, Kraebber K, Gamblin T, Guy L, George JF, Ayares D, Locke JE. Porrett PM, et al. Among authors: kuravi kv. Am J Transplant. 2022 Apr;22(4):1037-1053. doi: 10.1111/ajt.16930. Epub 2022 Jan 20. Am J Transplant. 2022. PMID: 35049121 Free article.
hEPCR.hTBM.hCD47.hHO-1 with donor clodronate and DDAVP treatment improves perfusion and function of GalTKO.hCD46 porcine livers perfused with human blood.
Cimeno A, Kuravi K, Sorrells L, Dandro A, Sendil S, Burdorf L, Parsell DM, Eyestone W, Phelps C, Ayares D, Azimzadeh AM, Pierson RN 3rd, Barth RN, LaMattina JC. Cimeno A, et al. Among authors: kuravi k. Xenotransplantation. 2022 Mar;29(2):e12731. doi: 10.1111/xen.12731. Epub 2022 Feb 15. Xenotransplantation. 2022. PMID: 35166407 Free PMC article.
Progressive genetic modifications of porcine cardiac xenografts extend survival to 9 months.
Mohiuddin MM, Goerlich CE, Singh AK, Zhang T, Tatarov I, Lewis B, Sentz F, Hershfeld A, Braileanu G, Odonkor P, Strauss E, Williams B, Burke A, Hittman J, Bhutta A, Tabatabai A, Gupta A, Vaught T, Sorrells L, Kuravi K, Dandro A, Eyestone W, Kaczorowski DJ, Ayares D, Griffith BP. Mohiuddin MM, et al. Among authors: kuravi k. Xenotransplantation. 2022 May;29(3):e12744. doi: 10.1111/xen.12744. Epub 2022 Mar 31. Xenotransplantation. 2022. PMID: 35357044 Free PMC article.
Knock-out of N-glycolylneuraminic acid attenuates antibody-mediated rejection in xenogenically perfused porcine lungs.
Chaban R, Habibabady Z, Hassanein W, Connolly MR, Burdorf L, Redding E, Laird C, Ranek J, Braileanu G, Sendil S, Cheng X, Sun W, O'Neill NA, Kuravi K, Hurh S, Ayares DL, Azimzadeh AM, Pierson RN 3rd. Chaban R, et al. Among authors: kuravi k. Xenotransplantation. 2022 Nov;29(6):e12784. doi: 10.1111/xen.12784. Epub 2022 Oct 17. Xenotransplantation. 2022. PMID: 36250568 Free PMC article.
Graft dysfunction in compassionate use of genetically engineered pig-to-human cardiac xenotransplantation: a case report.
Mohiuddin MM, Singh AK, Scobie L, Goerlich CE, Grazioli A, Saharia K, Crossan C, Burke A, Drachenberg C, Oguz C, Zhang T, Lewis B, Hershfeld A, Sentz F, Tatarov I, Mudd S, Braileanu G, Rice K, Paolini JF, Bondensgaard K, Vaught T, Kuravi K, Sorrells L, Dandro A, Ayares D, Lau C, Griffith BP. Mohiuddin MM, et al. Among authors: kuravi k. Lancet. 2023 Jul 29;402(10399):397-410. doi: 10.1016/S0140-6736(23)00775-4. Epub 2023 Jun 29. Lancet. 2023. PMID: 37393920
Expression of human thrombomodulin by GalTKO.hCD46 pigs modulates coagulation cascade activation by endothelial cells and during ex vivo lung perfusion with human blood.
Burdorf L, Gao Z, Riner A, Sievert E, Harris DG, Kuravi KV, Morrill BH, Habibabady Z, Rybak E, Dahi S, Zhang T, Schwartz E, Kang E, Cheng X, Esmon CT, Phelps CJ, Ayares DL, Iii RNP, Azimzadeh AM. Burdorf L, et al. Among authors: kuravi kv. Xenotransplantation. 2023 Nov-Dec;30(6):e12828. doi: 10.1111/xen.12828. Epub 2023 Sep 28. Xenotransplantation. 2023. PMID: 37767640
12 results