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Page 1
Hyperglycemia at 1h-OGTT in Pregnancy: A Reliable Predictor of Metabolic Outcomes?
Succurro E, Fraticelli F, Franzago M, Fiorentino TV, Andreozzi F, Vitacolonna E, Sesti G. Succurro E, et al. Among authors: sesti g. Front Endocrinol (Lausanne). 2021 May 24;12:612829. doi: 10.3389/fendo.2021.612829. eCollection 2021. Front Endocrinol (Lausanne). 2021. PMID: 34108933 Free PMC article. Review.
Chronic hyperglycemia impairs insulin secretion by affecting insulin receptor expression, splicing, and signaling in RIN beta cell line and human islets of Langerhans.
Hribal ML, Perego L, Lovari S, Andreozzi F, Menghini R, Perego C, Finzi G, Usellini L, Placidi C, Capella C, Guzzi V, Lauro D, Bertuzzi F, Davalli A, Pozza G, Pontiroli A, Federici M, Lauro R, Brunetti A, Folli F, Sesti G. Hribal ML, et al. Among authors: sesti g. FASEB J. 2003 Jul;17(10):1340-2. doi: 10.1096/fj.02-0685fje. Epub 2003 May 8. FASEB J. 2003. PMID: 12738810
Activation of the hexosamine pathway leads to phosphorylation of insulin receptor substrate-1 on Ser307 and Ser612 and impairs the phosphatidylinositol 3-kinase/Akt/mammalian target of rapamycin insulin biosynthetic pathway in RIN pancreatic beta-cells.
Andreozzi F, D'Alessandris C, Federici M, Laratta E, Del Guerra S, Del Prato S, Marchetti P, Lauro R, Perticone F, Sesti G. Andreozzi F, et al. Among authors: sesti g. Endocrinology. 2004 Jun;145(6):2845-57. doi: 10.1210/en.2003-0939. Epub 2004 Mar 4. Endocrinology. 2004. PMID: 15001544
Increased O-glycosylation of insulin signaling proteins results in their impaired activation and enhanced susceptibility to apoptosis in pancreatic beta-cells.
D'Alessandris C, Andreozzi F, Federici M, Cardellini M, Brunetti A, Ranalli M, Del Guerra S, Lauro D, Del Prato S, Marchetti P, Lauro R, Sesti G. D'Alessandris C, et al. Among authors: sesti g. FASEB J. 2004 Jun;18(9):959-61. doi: 10.1096/fj.03-0725fje. Epub 2004 Apr 1. FASEB J. 2004. PMID: 15059979
The -866A/A genotype in the promoter of the human uncoupling protein 2 gene is associated with insulin resistance and increased risk of type 2 diabetes.
D'Adamo M, Perego L, Cardellini M, Marini MA, Frontoni S, Andreozzi F, Sciacqua A, Lauro D, Sbraccia P, Federici M, Paganelli M, Pontiroli AE, Lauro R, Perticone F, Folli F, Sesti G. D'Adamo M, et al. Among authors: sesti g. Diabetes. 2004 Jul;53(7):1905-10. doi: 10.2337/diabetes.53.7.1905. Diabetes. 2004. PMID: 15220218
Impact of common polymorphisms in candidate genes for insulin resistance and obesity on weight loss of morbidly obese subjects after laparoscopic adjustable gastric banding and hypocaloric diet.
Sesti G, Perego L, Cardellini M, Andreozzi F, Ricasoli C, Vedani P, Guzzi V, Marchi M, Paganelli M, Ferla G, Pontiroli AE, Hribal ML, Folli F. Sesti G, et al. J Clin Endocrinol Metab. 2005 Sep;90(9):5064-9. doi: 10.1210/jc.2005-0404. Epub 2005 Jun 28. J Clin Endocrinol Metab. 2005. PMID: 15985484
488 results