Chronic hyperglycemia impairs insulin secretion by affecting insulin receptor expression, splicing, and signaling in RIN beta cell line and human islets of Langerhans.
Hribal ML, Perego L, Lovari S, Andreozzi F, Menghini R, Perego C, Finzi G, Usellini L, Placidi C, Capella C, Guzzi V, Lauro D, Bertuzzi F, Davalli A, Pozza G, Pontiroli A, Federici M, Lauro R, Brunetti A, Folli F, Sesti G.
Hribal ML, et al. Among authors: sesti g.
FASEB J. 2003 Jul;17(10):1340-2. doi: 10.1096/fj.02-0685fje. Epub 2003 May 8.
FASEB J. 2003.
PMID: 12738810