A 3-styrylchromone converted from trimebutine 3D pharmacophore possesses dual suppressive effects on RAGE and TLR4 signaling pathways.
Okazawa M, Oyama T, Abe H, Yamazaki H, Yoshimori A, Tsukimoto M, Yoshizawa K, Takao K, Sugita Y, Kamiya T, Uchiumi F, Sakagami H, Abe T, Tanuma SI.
Okazawa M, et al. Among authors: takao k.
Biochem Biophys Res Commun. 2021 Aug 20;566:1-8. doi: 10.1016/j.bbrc.2021.05.096. Epub 2021 Jun 7.
Biochem Biophys Res Commun. 2021.
PMID: 34111666