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Highly scalable arrayed CRISPR mediated gene silencing in primary lung small airway epithelial cells.
SLAS Discov. 2023 Mar;28(2):29-35. doi: 10.1016/j.slasd.2023.01.003. Epub 2023 Jan 14.
SLAS Discov. 2023.
PMID: 36649793
Free article.
A multi-parametric high throughput assay for detecting beta-cell proliferation in dispersed primary islets.
Mullooly N, Smith DM, Gianni D.
Mullooly N, et al.
SLAS Discov. 2023 Mar;28(2):3-12. doi: 10.1016/j.slasd.2023.01.002. Epub 2023 Jan 13.
SLAS Discov. 2023.
PMID: 36646173
Free article.
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CGRP, adrenomedullin and adrenomedullin 2 display endogenous GPCR agonist bias in primary human cardiovascular cells.
Clark AJ, Mullooly N, Safitri D, Harris M, de Vries T, MaassenVanDenBrink A, Poyner DR, Gianni D, Wigglesworth M, Ladds G.
Clark AJ, et al. Among authors: mullooly n.
Commun Biol. 2021 Jun 23;4(1):776. doi: 10.1038/s42003-021-02293-w.
Commun Biol. 2021.
PMID: 34163006
Free PMC article.
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High Seeding Density Induces Local Hypoxia and Triggers a Proinflammatory Response in Isolated Human Islets.
Brandhorst D, Brandhorst H, Mullooly N, Acreman S, Johnson PR.
Brandhorst D, et al. Among authors: mullooly n.
Cell Transplant. 2016;25(8):1539-46. doi: 10.3727/096368915X689929. Epub 2015 Nov 20.
Cell Transplant. 2016.
PMID: 26628048
Free article.
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Elevated levels of branched-chain amino acids have little effect on pancreatic islet cells, but L-arginine impairs function through activation of the endoplasmic reticulum stress response.
Mullooly N, Vernon W, Smith DM, Newsholme P.
Mullooly N, et al.
Exp Physiol. 2014 Mar;99(3):538-51. doi: 10.1113/expphysiol.2013.077495. Epub 2013 Dec 13.
Exp Physiol. 2014.
PMID: 24334335
Free article.
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Activation of the NLRP3 inflammasome by islet amyloid polypeptide provides a mechanism for enhanced IL-1β in type 2 diabetes.
Masters SL, Dunne A, Subramanian SL, Hull RL, Tannahill GM, Sharp FA, Becker C, Franchi L, Yoshihara E, Chen Z, Mullooly N, Mielke LA, Harris J, Coll RC, Mills KH, Mok KH, Newsholme P, Nuñez G, Yodoi J, Kahn SE, Lavelle EC, O'Neill LA.
Masters SL, et al. Among authors: mullooly n.
Nat Immunol. 2010 Oct;11(10):897-904. doi: 10.1038/ni.1935. Epub 2010 Sep 12.
Nat Immunol. 2010.
PMID: 20835230
Free PMC article.
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