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Page 1
NUDT15 polymorphisms alter thiopurine metabolism and hematopoietic toxicity.
Moriyama T, Nishii R, Perez-Andreu V, Yang W, Klussmann FA, Zhao X, Lin TN, Hoshitsuki K, Nersting J, Kihira K, Hofmann U, Komada Y, Kato M, McCorkle R, Li L, Koh K, Najera CR, Kham SK, Isobe T, Chen Z, Chiew EK, Bhojwani D, Jeffries C, Lu Y, Schwab M, Inaba H, Pui CH, Relling MV, Manabe A, Hori H, Schmiegelow K, Yeoh AE, Evans WE, Yang JJ. Moriyama T, et al. Among authors: yang jj, yang w. Nat Genet. 2016 Apr;48(4):367-73. doi: 10.1038/ng.3508. Epub 2016 Feb 15. Nat Genet. 2016. PMID: 26878724 Free PMC article.
Pharmacogenomics in acute lymphoblastic leukemia.
Lee SHR, Yang JJ. Lee SHR, et al. Among authors: yang jj. Best Pract Res Clin Haematol. 2017 Sep;30(3):229-236. doi: 10.1016/j.beha.2017.07.007. Epub 2017 Jul 27. Best Pract Res Clin Haematol. 2017. PMID: 29050696 Review.
Clinical Pharmacogenetics Implementation Consortium Guideline for Thiopurine Dosing Based on TPMT and NUDT15 Genotypes: 2018 Update.
Relling MV, Schwab M, Whirl-Carrillo M, Suarez-Kurtz G, Pui CH, Stein CM, Moyer AM, Evans WE, Klein TE, Antillon-Klussmann FG, Caudle KE, Kato M, Yeoh AEJ, Schmiegelow K, Yang JJ. Relling MV, et al. Among authors: yang jj. Clin Pharmacol Ther. 2019 May;105(5):1095-1105. doi: 10.1002/cpt.1304. Epub 2019 Jan 20. Clin Pharmacol Ther. 2019. PMID: 30447069 Free PMC article.
Massively parallel variant characterization identifies NUDT15 alleles associated with thiopurine toxicity.
Suiter CC, Moriyama T, Matreyek KA, Yang W, Scaletti ER, Nishii R, Yang W, Hoshitsuki K, Singh M, Trehan A, Parish C, Smith C, Li L, Bhojwani D, Yuen LYP, Li CK, Li CH, Yang YL, Walker GJ, Goodhand JR, Kennedy NA, Klussmann FA, Bhatia S, Relling MV, Kato M, Hori H, Bhatia P, Ahmad T, Yeoh AEJ, Stenmark P, Fowler DM, Yang JJ. Suiter CC, et al. Among authors: yang yl, yang jj, yang w. Proc Natl Acad Sci U S A. 2020 Mar 10;117(10):5394-5401. doi: 10.1073/pnas.1915680117. Epub 2020 Feb 24. Proc Natl Acad Sci U S A. 2020. PMID: 32094176 Free PMC article.
Molecular basis of ETV6-mediated predisposition to childhood acute lymphoblastic leukemia.
Nishii R, Baskin-Doerfler R, Yang W, Oak N, Zhao X, Yang W, Hoshitsuki K, Bloom M, Verbist K, Burns M, Li Z, Lin TN, Qian M, Moriyama T, Gastier-Foster JM, Rabin KR, Raetz E, Mullighan C, Pui CH, Yeoh AE, Zhang J, Metzger ML, Klco JM, Hunger SP, Newman S, Wu G, Loh ML, Nichols KE, Yang JJ. Nishii R, et al. Among authors: yang jj, yang w. Blood. 2021 Jan 21;137(3):364-373. doi: 10.1182/blood.2020006164. Blood. 2021. PMID: 32693409 Free PMC article.
Pharmacogenomics and ALL treatment: How to optimize therapy.
Karol SE, Yang JJ. Karol SE, et al. Among authors: yang jj. Semin Hematol. 2020 Jul;57(3):130-136. doi: 10.1053/j.seminhematol.2020.10.001. Epub 2020 Oct 20. Semin Hematol. 2020. PMID: 33256902 Free PMC article. Review.
Long-read HiFi sequencing of NUDT15: Phased full-gene haplotyping and pharmacogenomic allele discovery.
Scott ER, Yang Y, Botton MR, Seki Y, Hoshitsuki K, Harting J, Baybayan P, Cody N, Nicoletti P, Moriyama T, Chakraborty S, Yang JJ, Edelmann L, Schadt EE, Korlach J, Scott SA. Scott ER, et al. Among authors: yang jj, yang y. Hum Mutat. 2022 Nov;43(11):1557-1566. doi: 10.1002/humu.24457. Epub 2022 Sep 12. Hum Mutat. 2022. PMID: 36057977 Free PMC article.
2,214 results