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811 results

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Page 1
Oncogenic Rag GTPase signaling enhances B cell activation and drives follicular lymphoma sensitive to pharmacological inhibition of mTOR.
Ortega-Molina A, Deleyto-Seldas N, Carreras J, Sanz A, Lebrero-Fernández C, Menéndez C, Vandenberg A, Fernández-Ruiz B, Marín-Arraiza L, de la Calle Arregui C, Belén Plata-Gómez A, Caleiras E, de Martino A, Martínez-Martín N, Troulé K, Piñeiro-Yáñez E, Nakamura N, Araf S, Victora GD, Okosun J, Fitzgibbon J, Efeyan A. Ortega-Molina A, et al. Among authors: sanz a. Nat Metab. 2019 Aug;1(8):775-789. doi: 10.1038/s42255-019-0098-8. Epub 2019 Aug 19. Nat Metab. 2019. PMID: 31579886 Free PMC article.
Folliculin-interacting protein FNIP2 impacts on overweight and obesity through a polymorphism in a conserved 3' untranslated region.
Fernández LP, Deleyto-Seldas N, Colmenarejo G, Sanz A, Wagner S, Plata-Gómez AB, Gómez-Patiño M, Molina S, Espinosa-Salinas I, Aguilar-Aguilar E, Ortega S, Graña-Castro O, Loria-Kohen V, Fernández-Marcos PJ, Efeyan A, Ramírez de Molina A. Fernández LP, et al. Among authors: sanz a. Genome Biol. 2022 Oct 31;23(1):230. doi: 10.1186/s13059-022-02798-5. Genome Biol. 2022. PMID: 36316722 Free PMC article.
NGFR regulates stromal cell activation in germinal centers.
Hernández-Barranco A, Santos V, Mazariegos MS, Caleiras E, Nogués L, Mourcin F, Léonard S, Oblet C, Genebrier S, Rossille D, Benguría A, Sanz A, Vázquez E, Dopazo A, Efeyan A, Ortega-Molina A, Cogne M, Tarte K, Peinado H. Hernández-Barranco A, et al. Among authors: sanz a. Cell Rep. 2024 Feb 27;43(2):113705. doi: 10.1016/j.celrep.2024.113705. Epub 2024 Feb 1. Cell Rep. 2024. PMID: 38307025 Free article.
Hepatic nutrient and hormone signaling to mTORC1 instructs the postnatal metabolic zonation of the liver.
Plata-Gómez AB, de Prado-Rivas L, Sanz A, Deleyto-Seldas N, García F, de la Calle Arregui C, Silva C, Caleiras E, Graña-Castro O, Piñeiro-Yáñez E, Krebs J, Leiva-Vega L, Muñoz J, Jain A, Sabio G, Efeyan A. Plata-Gómez AB, et al. Among authors: sanz a. Nat Commun. 2024 Mar 18;15(1):1878. doi: 10.1038/s41467-024-46032-1. Nat Commun. 2024. PMID: 38499523 Free PMC article.
A mild increase in nutrient signaling to mTORC1 in mice leads to parenchymal damage, myeloid inflammation and shortened lifespan.
Ortega-Molina A, Lebrero-Fernández C, Sanz A, Calvo-Rubio M, Deleyto-Seldas N, de Prado-Rivas L, Plata-Gómez AB, Fernández-Florido E, González-García P, Vivas-García Y, Sánchez García E, Graña-Castro O, Price NL, Aroca-Crevillén A, Caleiras E, Monleón D, Borrás C, Casanova-Acebes M, de Cabo R, Efeyan A. Ortega-Molina A, et al. Among authors: sanz a. Nat Aging. 2024 Jun 7. doi: 10.1038/s43587-024-00635-x. Online ahead of print. Nat Aging. 2024. PMID: 38849535
Sphingosine kinase 1 overexpression induces MFN2 fragmentation and alters mitochondrial matrix Ca2+ handling in HeLa cells.
Pulli I, Löf C, Blom T, Asghar MY, Lassila T, Bäck N, Lin KL, Nyström JH, Kemppainen K, Toivola DM, Dufour E, Sanz A, Cooper HM, Parys JB, Törnquist K. Pulli I, et al. Among authors: sanz a. Biochim Biophys Acta Mol Cell Res. 2019 Sep;1866(9):1475-1486. doi: 10.1016/j.bbamcr.2019.06.006. Epub 2019 Jun 17. Biochim Biophys Acta Mol Cell Res. 2019. PMID: 31220477 Free article.
Tenecteplase versus alteplase for thrombolysis in patients selected by use of perfusion imaging within 4·5 h of onset of ischaemic stroke (TASTE): a multicentre, randomised, controlled, phase 3 non-inferiority trial.
Parsons MW, Yogendrakumar V, Churilov L, Garcia-Esperon C, Campbell BCV, Russell ML, Sharma G, Chen C, Lin L, Chew BL, Ng FC, Deepak A, Choi PMC, Kleinig TJ, Cordato DJ, Wu TY, Fink JN, Ma H, Phan TG, Markus HS, Molina CA, Tsai CH, Lee JT, Jeng JS, Strbian D, Meretoja A, Arenillas JF, Buck BH, Devlin MJ, Brown H, Butcher KS, O'Brien B, Sabet A, Wijeratne T, Bivard A, Grimley RS, Agarwal S, Munshi SK, Donnan GA, Davis SM, Miteff F, Spratt NJ, Levi CR; TASTE investigators. Parsons MW, et al. Lancet Neurol. 2024 Jun 13:S1474-4422(24)00206-0. doi: 10.1016/S1474-4422(24)00206-0. Online ahead of print. Lancet Neurol. 2024. PMID: 38880118
Broad protection against invasive fungal disease from a nanobody targeting the active site of fungal b-1,3-glucanosyltransferases.
Redrado-Hernández S, Macías-León J, Castro-López J, Sanz AB, Dolader E, Arias M, González-Ramírez AM, Sánchez-Navarro D, Petryk Y, Farkaš V, Vincke C, Muyldermans S, García-Barbazán I, Del Agua C, Zaragoza O, Arroyo J, Pardo J, Gálvez E, Hurtado-Guerrero R. Redrado-Hernández S, et al. Among authors: sanz ab. Angew Chem Int Ed Engl. 2024 Jun 10:e202405823. doi: 10.1002/anie.202405823. Online ahead of print. Angew Chem Int Ed Engl. 2024. PMID: 38856634
Laryngeal chondromas: Current knowledge and future directions.
Candelo E, Bohorquez Caballero AD, Abello-Vaamonde JA, Sanz AM, Lozano Gonzalez R, Chelf C, Williams AM, Rutt AL. Candelo E, et al. Among authors: sanz am. Laryngoscope Investig Otolaryngol. 2024 Jun 4;9(3):e1265. doi: 10.1002/lio2.1265. eCollection 2024 Jun. Laryngoscope Investig Otolaryngol. 2024. PMID: 38835336 Free PMC article. Review.
811 results