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A loss-of-function variant in SUV39H2 identified in autism-spectrum disorder causes altered H3K9 trimethylation and dysregulation of protocadherin β-cluster genes in the developing brain.
Balan S, Iwayama Y, Ohnishi T, Fukuda M, Shirai A, Yamada A, Weirich S, Schuhmacher MK, Dileep KV, Endo T, Hisano Y, Kotoshiba K, Toyota T, Otowa T, Kuwabara H, Tochigi M, Watanabe A, Ohba H, Maekawa M, Toyoshima M, Sasaki T, Nakamura K, Tsujii M, Matsuzaki H, Zhang KYJ, Jeltsch A, Shinkai Y, Yoshikawa T. Balan S, et al. Among authors: iwayama y. Mol Psychiatry. 2021 Dec;26(12):7550-7559. doi: 10.1038/s41380-021-01199-7. Epub 2021 Jul 15. Mol Psychiatry. 2021. PMID: 34262135
Functional characterization of FABP3, 5 and 7 gene variants identified in schizophrenia and autism spectrum disorder and mouse behavioral studies.
Shimamoto C, Ohnishi T, Maekawa M, Watanabe A, Ohba H, Arai R, Iwayama Y, Hisano Y, Toyota T, Toyoshima M, Suzuki K, Shirayama Y, Nakamura K, Mori N, Owada Y, Kobayashi T, Yoshikawa T. Shimamoto C, et al. Among authors: iwayama y. Hum Mol Genet. 2014 Dec 15;23(24):6495-511. doi: 10.1093/hmg/ddu369. Epub 2014 Jul 15. Hum Mol Genet. 2014. PMID: 25027319 Free PMC article.
Protocadherin α (PCDHA) as a novel susceptibility gene for autism.
Anitha A, Thanseem I, Nakamura K, Yamada K, Iwayama Y, Toyota T, Iwata Y, Suzuki K, Sugiyama T, Tsujii M, Yoshikawa T, Mori N. Anitha A, et al. Among authors: iwayama y. J Psychiatry Neurosci. 2013 May;38(3):192-8. doi: 10.1503/jpn.120058. J Psychiatry Neurosci. 2013. PMID: 23031252 Free PMC article.
Association of transcription factor gene LMX1B with autism.
Thanseem I, Nakamura K, Anitha A, Suda S, Yamada K, Iwayama Y, Toyota T, Tsujii M, Iwata Y, Suzuki K, Matsuzaki H, Iwata K, Sugiyama T, Yoshikawa T, Mori N. Thanseem I, et al. Among authors: iwayama y. PLoS One. 2011;6(8):e23738. doi: 10.1371/journal.pone.0023738. Epub 2011 Aug 25. PLoS One. 2011. PMID: 21901133 Free PMC article.
Brain region-specific altered expression and association of mitochondria-related genes in autism.
Anitha A, Nakamura K, Thanseem I, Yamada K, Iwayama Y, Toyota T, Matsuzaki H, Miyachi T, Yamada S, Tsujii M, Tsuchiya KJ, Matsumoto K, Iwata Y, Suzuki K, Ichikawa H, Sugiyama T, Yoshikawa T, Mori N. Anitha A, et al. Among authors: iwayama y. Mol Autism. 2012 Nov 1;3(1):12. doi: 10.1186/2040-2392-3-12. Mol Autism. 2012. PMID: 23116158 Free PMC article.
A population-specific uncommon variant in GRIN3A associated with schizophrenia.
Takata A, Iwayama Y, Fukuo Y, Ikeda M, Okochi T, Maekawa M, Toyota T, Yamada K, Hattori E, Ohnishi T, Toyoshima M, Ujike H, Inada T, Kunugi H, Ozaki N, Nanko S, Nakamura K, Mori N, Kanba S, Iwata N, Kato T, Yoshikawa T. Takata A, et al. Among authors: iwayama y. Biol Psychiatry. 2013 Mar 15;73(6):532-9. doi: 10.1016/j.biopsych.2012.10.024. Epub 2012 Dec 11. Biol Psychiatry. 2013. PMID: 23237318 Free article.
Zinc finger protein 804A (ZNF804A) and verbal deficits in individuals with autism.
Anitha A, Thanseem I, Nakamura K, Vasu MM, Yamada K, Ueki T, Iwayama Y, Toyota T, Tsuchiya KJ, Iwata Y, Suzuki K, Sugiyama T, Tsujii M, Yoshikawa T, Mori N. Anitha A, et al. Among authors: iwayama y. J Psychiatry Neurosci. 2014 Sep;39(5):294-303. doi: 10.1503/jpn.130126. J Psychiatry Neurosci. 2014. PMID: 24866414 Free PMC article.
199 results