Sulforaphane, an NRF2 agonist, alleviates ferroptosis in acute liver failure by regulating HDAC6 activity.
Zhang YQ, Shi CX, Zhang DM, Zhang LY, Wang LW, Gong ZJ.
Zhang YQ, et al. Among authors: zhang dm, zhang ly.
J Integr Med. 2023 Sep;21(5):464-473. doi: 10.1016/j.joim.2023.08.002. Epub 2023 Aug 9.
J Integr Med. 2023.
PMID: 37620223
CONCLUSION: SFN has a protective effect on ALF, and the mechanism may include reduction of ferroptosis through the regulation of HDAC6. Please cite this article as: Zhang YQ, Shi CX, Zhang DM, Zhang LY, Wang LW, Gong ZJ. Sulforaphane, an NRF2 agonist, …
CONCLUSION: SFN has a protective effect on ALF, and the mechanism may include reduction of ferroptosis through the regulation of HDAC6. Plea …