Lebrec H - Search Results

1

Non-clinical similarity of biosimilar ABP 798 with rituximab reference product.

McBride HJ, Jassem S, Chow V, Kanakaraj P, Lebrec H, Kuhns S, Ferbas J, Wong M, Thway TM. McBride HJ, et al. Among authors: lebrec h. Biologicals. 2021 Jul;72:42-53. doi: 10.1016/j.biologicals.2021.05.002. Epub 2021 Jul 21. Biologicals. 2021. PMID: 34303595 Free article.

2

Use of nonclinical toxicity studies to support biosimilar antibody development.

Mihalcik L, Chow V, Ramchandani M, Hinkle B, McBride HJ, Lebrec H. Mihalcik L, et al. Among authors: lebrec h. Regul Toxicol Pharmacol. 2021 Jun;122:104912. doi: 10.1016/j.yrtph.2021.104912. Epub 2021 Mar 1. Regul Toxicol Pharmacol. 2021. PMID: 33662478 No abstract available.

3

Strategies to evaluate potential effector function of glycan variants: a case study of ordesekimab (AMG 714 or PRV-015).

Wei YL, Wegesser T, Kuhns S, Werner J, Lebrec H, Wang X. Wei YL, et al. Among authors: lebrec h. J Immunotoxicol. 2022 Dec;19(1):109-116. doi: 10.1080/1547691X.2022.2113841. J Immunotoxicol. 2022. PMID: 36083248 Review.

4

Current Concepts in Natural Killer Cell Biology and Application to Drug Safety Assessments.

Goyos A, Fort M, Sharma A, Lebrec H. Goyos A, et al. Among authors: lebrec h. Toxicol Sci. 2019 Jul 1;170(1):10-19. doi: 10.1093/toxsci/kfz098. Toxicol Sci. 2019. PMID: 31020324 Review.

5

Development of a BiTE^®-mediated CD8⁺ cytotoxic T-lymphocyte activity assay to assess immunomodulatory potential of drug candidates in Cynomolgus macaque.

Frank B, Wei YL, Kim KH, Guerrero A, Lebrec H, Balazs M, Wang X. Frank B, et al. Among authors: lebrec h. J Immunotoxicol. 2018 Dec;15(1):119-125. doi: 10.1080/1547691X.2018.1486342. J Immunotoxicol. 2018. PMID: 30241454

6

Application of a newly-developed cynomolgus macaque BiTE-mediated cytotoxic T-lymphocyte activity assay to various immunomodulatory agents in vitro.

Frank B, Guo H, Lebrec H, Wang X. Frank B, et al. Among authors: lebrec h. J Immunotoxicol. 2021 Dec;18(1):154-162. doi: 10.1080/1547691X.2021.1992687. J Immunotoxicol. 2021. PMID: 34714999

7

Immunophenotyping: Application to Safety Assessment.

Wang X, Lebrec H. Wang X, et al. Among authors: lebrec h. Toxicol Pathol. 2017 Oct;45(7):1004-1011. doi: 10.1177/0192623317736742. Epub 2017 Nov 2. Toxicol Pathol. 2017. PMID: 29096594

8

GIPR gene expression in testis is mouse specific and can impact male mouse fertility.

Killion EA, Hussien R, Shkumatov A, Davies R, Lloyd DJ, Véniant MM, Lebrec H, Fort MM. Killion EA, et al. Among authors: lebrec h. Andrology. 2022 May;10(4):789-799. doi: 10.1111/andr.13166. Epub 2022 Mar 8. Andrology. 2022. PMID: 35224888 Free article.

9

Characterization of an Anti-CD70 Half-Life Extended Bispecific T-Cell Engager (HLE-BiTE) and Associated On-Target Toxicity in Cynomolgus Monkeys.

Harper T, Sharma A, Kaliyaperumal S, Fajardo F, Hsu K, Liu L, Davies R, Wei YL, Zhan J, Estrada J, Kvesic M, Nahrwold L, Deisting W, Panzer M, Cooke K, Lebrec H, Nolan-Stevaux O. Harper T, et al. Among authors: lebrec h. Toxicol Sci. 2022 Aug 25;189(1):32-50. doi: 10.1093/toxsci/kfac052. Toxicol Sci. 2022. PMID: 35583313

10

Homeostasis of human NK cells is not IL-15 dependent.

Lebrec H, Horner MJ, Gorski KS, Tsuji W, Xia D, Pan WJ, Means G, Pietz G, Li N, Retter M, Shaffer K, Patel N, Narayanan PK, Butz EA. Lebrec H, et al. J Immunol. 2013 Dec 1;191(11):5551-8. doi: 10.4049/jimmunol.1301000. Epub 2013 Nov 1. J Immunol. 2013. PMID: 24184554

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