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Characterizing the genetic basis of innate immune response in TLR4-activated human monocytes.
Kim S, Becker J, Bechheim M, Kaiser V, Noursadeghi M, Fricker N, Beier E, Klaschik S, Boor P, Hess T, Hofmann A, Holdenrieder S, Wendland JR, Fröhlich H, Hartmann G, Nöthen MM, Müller-Myhsok B, Pütz B, Hornung V, Schumacher J. Kim S, et al. Among authors: hornung v. Nat Commun. 2014 Oct 20;5:5236. doi: 10.1038/ncomms6236. Nat Commun. 2014. PMID: 25327457 Free article.
Genetic regulatory effects modified by immune activation contribute to autoimmune disease associations.
Kim-Hellmuth S, Bechheim M, Pütz B, Mohammadi P, Nédélec Y, Giangreco N, Becker J, Kaiser V, Fricker N, Beier E, Boor P, Castel SE, Nöthen MM, Barreiro LB, Pickrell JK, Müller-Myhsok B, Lappalainen T, Schumacher J, Hornung V. Kim-Hellmuth S, et al. Among authors: hornung v. Nat Commun. 2017 Aug 16;8(1):266. doi: 10.1038/s41467-017-00366-1. Nat Commun. 2017. PMID: 28814792 Free PMC article.
IRF1 Inhibits Antitumor Immunity through the Upregulation of PD-L1 in the Tumor Cell.
Shao L, Hou W, Scharping NE, Vendetti FP, Srivastava R, Roy CN, Menk AV, Wang Y, Chauvin JM, Karukonda P, Thorne SH, Hornung V, Zarour HM, Bakkenist CJ, Delgoffe GM, Sarkar SN. Shao L, et al. Among authors: hornung v. Cancer Immunol Res. 2019 Aug;7(8):1258-1266. doi: 10.1158/2326-6066.CIR-18-0711. Epub 2019 Jun 25. Cancer Immunol Res. 2019. PMID: 31239318 Free PMC article.
Immune homeostasis and regulation of the interferon pathway require myeloid-derived Regnase-3.
von Gamm M, Schaub A, Jones AN, Wolf C, Behrens G, Lichti J, Essig K, Macht A, Pircher J, Ehrlich A, Davari K, Chauhan D, Busch B, Wurst W, Feederle R, Feuchtinger A, Tschöp MH, Friedel CC, Hauck SM, Sattler M, Geerlof A, Hornung V, Heissmeyer V, Schulz C, Heikenwalder M, Glasmacher E. von Gamm M, et al. Among authors: hornung v. J Exp Med. 2019 Jul 1;216(7):1700-1723. doi: 10.1084/jem.20181762. Epub 2019 May 24. J Exp Med. 2019. PMID: 31126966 Free PMC article.
C-tag TNF: a reporter system to study TNF shedding.
Pinci F, Gaidt MM, Jung C, Kuut G, Jackson MA, Bauernfried S, Hornung V. Pinci F, et al. Among authors: hornung v. J Biol Chem. 2020 Dec 25;295(52):18065-18075. doi: 10.1074/jbc.RA120.015248. Epub 2020 Oct 20. J Biol Chem. 2020. PMID: 33082141 Free PMC article.
Human NLRP1: From the shadows to center stage.
Bauernfried S, Hornung V. Bauernfried S, et al. Among authors: hornung v. J Exp Med. 2022 Jan 3;219(1):e20211405. doi: 10.1084/jem.20211405. Epub 2021 Dec 15. J Exp Med. 2022. PMID: 34910085 Free PMC article. Review.
214 results