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Inhibiting pyrimidine biosynthesis impairs Ebola virus replication through depletion of nucleoside pools and activation of innate immune responses.
Luthra P, Naidoo J, Pietzsch CA, De S, Khadka S, Anantpadma M, Williams CG, Edwards MR, Davey RA, Bukreyev A, Ready JM, Basler CF. Luthra P, et al. Among authors: williams cg. Antiviral Res. 2018 Oct;158:288-302. doi: 10.1016/j.antiviral.2018.08.012. Epub 2018 Aug 23. Antiviral Res. 2018. PMID: 30144461 Free PMC article.
Non-canonical proline-tyrosine interactions with multiple host proteins regulate Ebola virus infection.
Batra J, Mori H, Small GI, Anantpadma M, Shtanko O, Mishra N, Zhang M, Liu D, Williams CG, Biedenkopf N, Becker S, Gross ML, Leung DW, Davey RA, Amarasinghe GK, Krogan NJ, Basler CF. Batra J, et al. Among authors: williams cg. EMBO J. 2021 Sep 15;40(18):e105658. doi: 10.15252/embj.2020105658. Epub 2021 Aug 2. EMBO J. 2021. PMID: 34260076 Free PMC article.
Synthesis and antiviral activity of fatty acyl conjugates of remdesivir against severe acute respiratory syndrome coronavirus 2 and Ebola virus.
El-Sayed NS, Jureka AS, Edwards MR, Lohan S, Williams CG, Keiser PT, Davey RA, Totonchy J, Tiwari RK, Basler CF, Parang K. El-Sayed NS, et al. Among authors: williams cg. Eur J Med Chem. 2021 Dec 15;226:113862. doi: 10.1016/j.ejmech.2021.113862. Epub 2021 Sep 21. Eur J Med Chem. 2021. PMID: 34583312 Free PMC article.
Plasmodium infection induces phenotypic, clonal, and spatial diversity among differentiating CD4+ T cells.
Williams CG, Moreira ML, Asatsuma T, Lee HJ, Li S, Barrera I, Murray E, Soon MSF, Engel JA, Khoury DS, Le S, Wanrooy BJ, Schienstock D, Alexandre YO, Skinner OP, Joseph R, Beattie L, Mueller SN, Chen F, Haque A. Williams CG, et al. Cell Rep. 2024 Jun 5;43(6):114317. doi: 10.1016/j.celrep.2024.114317. Online ahead of print. Cell Rep. 2024. PMID: 38848213 Free article.
162 results