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Production of Proteins of the SARS-CoV-2 Proteome for Drug Discovery.
Kim C, Mahasenan KV, Bhardwaj A, Wiest O, Chang M, Mobashery S. Kim C, et al. Among authors: wiest o. ACS Omega. 2021 Jul 20;6(30):19983-19994. doi: 10.1021/acsomega.1c02984. eCollection 2021 Aug 3. ACS Omega. 2021. PMID: 34337272 Free PMC article.
Design, Synthesis, and Evaluation of a Luminescent Cholesterol Mimic.
Work EM, Ferraudi G, Kiefer L, Liu G, Grigalunas M, Bhardwaj A, Kaur R, Dempsey JM, Wüstner D, Helquist P, Wiest O. Work EM, et al. Among authors: wiest o. J Org Chem. 2021 Jan 15;86(2):1612-1621. doi: 10.1021/acs.joc.0c02460. Epub 2020 Dec 28. J Org Chem. 2021. PMID: 33369429 Free PMC article.
Targeting the chromatin effector Pygo2 promotes cytotoxic T cell responses and overcomes immunotherapy resistance in prostate cancer.
Zhu Y, Zhao Y, Wen J, Liu S, Huang T, Hatial I, Peng X, Al Janabi H, Huang G, Mittlesteadt J, Cheng M, Bhardwaj A, Ashfeld BL, Kao KR, Maeda DY, Dai X, Wiest O, Blagg BSJ, Lu X, Cheng L, Wan J, Lu X. Zhu Y, et al. Among authors: wiest o. Sci Immunol. 2023 Mar 17;8(81):eade4656. doi: 10.1126/sciimmunol.ade4656. Epub 2023 Mar 10. Sci Immunol. 2023. PMID: 36897957 Free PMC article.
Inhibition of Histone Deacetylases 1, 2, and 3 Enhances Clearance of Cholesterol Accumulation in Niemann-Pick C1 Fibroblasts.
Cruz DL, Pipalia N, Mao S, Gadi D, Liu G, Grigalunas M, O'Neill M, Quinn TR, Kipper A, Ekebergh A, Dimmling A, Gartner C, Melancon BJ, Wagner FF, Holson E, Helquist P, Wiest O, Maxfield FR. Cruz DL, et al. Among authors: wiest o, o neill m. ACS Pharmacol Transl Sci. 2021 May 27;4(3):1136-1148. doi: 10.1021/acsptsci.1c00033. eCollection 2021 Jun 11. ACS Pharmacol Transl Sci. 2021. PMID: 34151204 Free PMC article.
Blueprint for antimicrobial hit discovery targeting metabolic networks.
Shen Y, Liu J, Estiu G, Isin B, Ahn YY, Lee DS, Barabási AL, Kapatral V, Wiest O, Oltvai ZN. Shen Y, et al. Among authors: wiest o. Proc Natl Acad Sci U S A. 2010 Jan 19;107(3):1082-7. doi: 10.1073/pnas.0909181107. Epub 2010 Jan 5. Proc Natl Acad Sci U S A. 2010. PMID: 20080587 Free PMC article.
151 results