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Discovery of a dual Ras and ARF6 inhibitor from a GPCR endocytosis screen.
Giubilaro J, Schuetz DA, Stepniewski TM, Namkung Y, Khoury E, Lara-Márquez M, Campbell S, Beautrait A, Armando S, Radresa O, Duchaine J, Lamarche-Vane N, Claing A, Selent J, Bouvier M, Marinier A, Laporte SA. Giubilaro J, et al. Among authors: selent j. Nat Commun. 2021 Aug 3;12(1):4688. doi: 10.1038/s41467-021-24968-y. Nat Commun. 2021. PMID: 34344896 Free PMC article.
Palmitoylation of cysteine 415 of CB1 receptor affects ligand-stimulated internalization and selective interaction with membrane cholesterol and caveolin 1.
Oddi S, Stepniewski TM, Totaro A, Selent J, Scipioni L, Dufrusine B, Fezza F, Dainese E, Maccarrone M. Oddi S, et al. Among authors: selent j. Biochim Biophys Acta Mol Cell Biol Lipids. 2017 May;1862(5):523-532. doi: 10.1016/j.bbalip.2017.02.004. Epub 2017 Feb 12. Biochim Biophys Acta Mol Cell Biol Lipids. 2017. PMID: 28215712
C-edge loops of arrestin function as a membrane anchor.
Lally CC, Bauer B, Selent J, Sommer ME. Lally CC, et al. Among authors: selent j. Nat Commun. 2017 Feb 21;8:14258. doi: 10.1038/ncomms14258. Nat Commun. 2017. PMID: 28220785 Free PMC article.
Membrane cholesterol access into a G-protein-coupled receptor.
Guixà-González R, Albasanz JL, Rodriguez-Espigares I, Pastor M, Sanz F, Martí-Solano M, Manna M, Martinez-Seara H, Hildebrand PW, Martín M, Selent J. Guixà-González R, et al. Among authors: selent j. Nat Commun. 2017 Feb 21;8:14505. doi: 10.1038/ncomms14505. Nat Commun. 2017. PMID: 28220900 Free PMC article.
Challenges and Opportunities in Drug Discovery of Biased Ligands.
Rodríguez-Espigares I, Kaczor AA, Stepniewski TM, Selent J. Rodríguez-Espigares I, et al. Among authors: selent j. Methods Mol Biol. 2018;1705:321-334. doi: 10.1007/978-1-4939-7465-8_14. Methods Mol Biol. 2018. PMID: 29188569 Review.
Protein-Protein Docking in Drug Design and Discovery.
Kaczor AA, Bartuzi D, Stępniewski TM, Matosiuk D, Selent J. Kaczor AA, et al. Among authors: selent j. Methods Mol Biol. 2018;1762:285-305. doi: 10.1007/978-1-4939-7756-7_15. Methods Mol Biol. 2018. PMID: 29594778
88 results