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Synthesis and Biological Assessment of 4,1-Benzothiazepines with Neuroprotective Activity on the Ca2+ Overload for the Treatment of Neurodegenerative Diseases and Stroke.
Viejo L, Rubio-Alarcón M, Arribas RL, Moreno-Castro M, Pérez-Marín R, Braun-Cornejo M, Estrada-Valencia M, de Los Ríos C. Viejo L, et al. Among authors: estrada valencia m. Molecules. 2021 Jul 24;26(15):4473. doi: 10.3390/molecules26154473. Molecules. 2021. PMID: 34361628 Free PMC article.
Resveratrol-Based MTDLs to Stimulate Defensive and Regenerative Pathways and Block Early Events in Neurodegenerative Cascades.
Herrera-Arozamena C, Estrada-Valencia M, López-Caballero P, Pérez C, Morales-García JA, Pérez-Castillo A, Sastre ED, Fernández-Mendívil C, Duarte P, Michalska P, Lombardía J, Senar S, León R, López MG, Rodríguez-Franco MI. Herrera-Arozamena C, et al. Among authors: estrada valencia m. J Med Chem. 2022 Mar 24;65(6):4727-4751. doi: 10.1021/acs.jmedchem.1c01883. Epub 2022 Mar 4. J Med Chem. 2022. PMID: 35245051 Free PMC article.
Tuning melatonin receptor subtype selectivity in oxadiazolone-based analogues: Discovery of QR2 ligands and NRF2 activators with neurogenic properties.
Herrera-Arozamena C, Estrada-Valencia M, Pérez C, Lagartera L, Morales-García JA, Pérez-Castillo A, Franco-Gonzalez JF, Michalska P, Duarte P, León R, López MG, Mills A, Gago F, García-Yagüe ÁJ, Fernández-Ginés R, Cuadrado A, Rodríguez-Franco MI. Herrera-Arozamena C, et al. Among authors: estrada valencia m. Eur J Med Chem. 2020 Mar 15;190:112090. doi: 10.1016/j.ejmech.2020.112090. Epub 2020 Jan 25. Eur J Med Chem. 2020. PMID: 32018096 Free article.
Neurogenic and neuroprotective donepezil-flavonoid hybrids with sigma-1 affinity and inhibition of key enzymes in Alzheimer's disease.
Estrada Valencia M, Herrera-Arozamena C, de Andrés L, Pérez C, Morales-García JA, Pérez-Castillo A, Ramos E, Romero A, Viña D, Yáñez M, Laurini E, Pricl S, Rodríguez-Franco MI. Estrada Valencia M, et al. Eur J Med Chem. 2018 Aug 5;156:534-553. doi: 10.1016/j.ejmech.2018.07.026. Epub 2018 Jul 11. Eur J Med Chem. 2018. PMID: 30025348 Free article.
New flavonoid - N,N-dibenzyl(N-methyl)amine hybrids: Multi-target-directed agents for Alzheimer´s disease endowed with neurogenic properties.
Estrada-Valencia M, Herrera-Arozamena C, Pérez C, Viña D, Morales-García JA, Pérez-Castillo A, Ramos E, Romero A, Laurini E, Pricl S, Rodríguez-Franco MI. Estrada-Valencia M, et al. J Enzyme Inhib Med Chem. 2019 Dec;34(1):712-727. doi: 10.1080/14756366.2019.1581184. J Enzyme Inhib Med Chem. 2019. PMID: 31852270 Free PMC article.
Optical control of muscular nicotinic channels with azocuroniums, photoswitchable azobenzenes bearing two N-methyl-N-carbocyclic quaternary ammonium groups.
Herrera-Arozamena C, Estrada-Valencia M, Martí-Marí O, Pérez C, de la Fuente Revenga M, Villalba-Galea CA, Rodríguez-Franco MI. Herrera-Arozamena C, et al. Among authors: estrada valencia m. Eur J Med Chem. 2020 Aug 15;200:112403. doi: 10.1016/j.ejmech.2020.112403. Epub 2020 May 13. Eur J Med Chem. 2020. PMID: 32447198