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The History of Flow Chemistry at Eli Lilly and Company.
Johnson MD, Braden T, Calvin JR, Campbell Brewer A, Cole KP, Frank S, Kerr M, Kjell D, Kopach ME, Martinelli JR, May SA, Rincón J, White TD, Yates MH. Johnson MD, et al. Among authors: frank s. Chimia (Aarau). 2023 May 31;77(5):319-326. doi: 10.2533/chimia.2023.319. Chimia (Aarau). 2023. PMID: 38047828 Free article.
A selective estrogen receptor modulator designed for the treatment of uterine leiomyoma with unique tissue specificity for uterus and ovaries in rats.
Hummel CW, Geiser AG, Bryant HU, Cohen IR, Dally RD, Fong KC, Frank SA, Hinklin R, Jones SA, Lewis G, McCann DJ, Rudmann DG, Shepherd TA, Tian H, Wallace OB, Wang M, Wang Y, Dodge JA. Hummel CW, et al. Among authors: frank sa. J Med Chem. 2005 Nov 3;48(22):6772-5. doi: 10.1021/jm050723z. J Med Chem. 2005. PMID: 16250633
Current and Future Roles of Artificial Intelligence in Medicinal Chemistry Synthesis.
Struble TJ, Alvarez JC, Brown SP, Chytil M, Cisar J, DesJarlais RL, Engkvist O, Frank SA, Greve DR, Griffin DJ, Hou X, Johannes JW, Kreatsoulas C, Lahue B, Mathea M, Mogk G, Nicolaou CA, Palmer AD, Price DJ, Robinson RI, Salentin S, Xing L, Jaakkola T, Green WH, Barzilay R, Coley CW, Jensen KF. Struble TJ, et al. Among authors: frank sa. J Med Chem. 2020 Aug 27;63(16):8667-8682. doi: 10.1021/acs.jmedchem.9b02120. Epub 2020 Apr 14. J Med Chem. 2020. PMID: 32243158 Free PMC article.
Structure-activity relationships of SERMs optimized for uterine antagonism and ovarian safety.
Richardson TI, Frank SA, Wang M, Clarke CA, Jones SA, Ying BP, Kohlman DT, Wallace OB, Shepherd TA, Dally RD, Palkowitz AD, Geiser AG, Bryant HU, Henck JW, Cohen IR, Rudmann DG, McCann DJ, Coutant DE, Oldham SW, Hummel CW, Fong KC, Hinklin R, Lewis G, Tian H, Dodge JA. Richardson TI, et al. Among authors: frank sa. Bioorg Med Chem Lett. 2007 Jul 1;17(13):3544-9. doi: 10.1016/j.bmcl.2007.04.044. Epub 2007 Apr 24. Bioorg Med Chem Lett. 2007. PMID: 17482463
Quantum Mechanical Assessment of Nitrosamine Potency.
De S, Thapa B, Sayyed FB, Frank SA, Cornwell PD, Jolly RA. De S, et al. Among authors: frank sa. Chem Res Toxicol. 2024 May 28. doi: 10.1021/acs.chemrestox.4c00087. Online ahead of print. Chem Res Toxicol. 2024. PMID: 38804898
Robustness and complexity.
Frank SA. Frank SA. Cell Syst. 2023 Dec 20;14(12):1015-1020. doi: 10.1016/j.cels.2023.11.003. Cell Syst. 2023. PMID: 38128480
185 results