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Analysis of complex protein elution behavior in preparative ion exchange processes using a colloidal particle adsorption model.
J Chromatogr A. 2021 Sep 27;1654:462439. doi: 10.1016/j.chroma.2021.462439. Epub 2021 Jul 24.
J Chromatogr A. 2021.
PMID: 34384923
Adsorption of colloidal proteins in ion-exchange chromatography under consideration of charge regulation.
Briskot T, Hahn T, Huuk T, Hubbuch J.
Briskot T, et al. Among authors: huuk t.
J Chromatogr A. 2020 Jan 25;1611:460608. doi: 10.1016/j.chroma.2019.460608. Epub 2019 Oct 9.
J Chromatogr A. 2020.
PMID: 31629491
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Protein adsorption on ion exchange adsorbers: A comparison of a stoichiometric and non-stoichiometric modeling approach.
Briskot T, Hahn T, Huuk T, Hubbuch J.
Briskot T, et al. Among authors: huuk t.
J Chromatogr A. 2021 Sep 13;1653:462397. doi: 10.1016/j.chroma.2021.462397. Epub 2021 Jul 9.
J Chromatogr A. 2021.
PMID: 34284263
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A versatile noninvasive method for adsorber quantification in batch and column chromatography based on the ionic capacity.
Huuk TC, Briskot T, Hahn T, Hubbuch J.
Huuk TC, et al.
Biotechnol Prog. 2016 May;32(3):666-77. doi: 10.1002/btpr.2228. Epub 2016 Feb 26.
Biotechnol Prog. 2016.
PMID: 27324662
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Modeling of complex antibody elution behavior under high protein load densities in ion exchange chromatography using an asymmetric activity coefficient.
Huuk TC, Hahn T, Doninger K, Griesbach J, Hepbildikler S, Hubbuch J.
Huuk TC, et al.
Biotechnol J. 2017 Mar;12(3). doi: 10.1002/biot.201600336. Epub 2017 Feb 9.
Biotechnol J. 2017.
PMID: 27976534
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