Geurink PP - Search Results

1

Development of Tyrphostin Analogues to Study Inhibition of the Mycobacterium tuberculosis Pup Proteasome System*.

Janssen GV, Zhang S, Merkx R, Schiesswohl C, Chatterjee C, Darwin KH, Geurink PP, van der Heden van Noort GJ, Ovaa H. Janssen GV, et al. Among authors: geurink pp. Chembiochem. 2021 Nov 3;22(21):3082-3089. doi: 10.1002/cbic.202100333. Epub 2021 Sep 12. Chembiochem. 2021. PMID: 34387015 Free PMC article.

2

The differential modulation of USP activity by internal regulatory domains, interactors and eight ubiquitin chain types.

Faesen AC, Luna-Vargas MP, Geurink PP, Clerici M, Merkx R, van Dijk WJ, Hameed DS, El Oualid F, Ovaa H, Sixma TK. Faesen AC, et al. Among authors: geurink pp. Chem Biol. 2011 Dec 23;18(12):1550-61. doi: 10.1016/j.chembiol.2011.10.017. Chem Biol. 2011. PMID: 22195557

3

A general chemical ligation approach towards isopeptide-linked ubiquitin and ubiquitin-like assay reagents.

Geurink PP, El Oualid F, Jonker A, Hameed DS, Ovaa H. Geurink PP, et al. Chembiochem. 2012 Jan 23;13(2):293-7. doi: 10.1002/cbic.201100706. Epub 2011 Dec 23. Chembiochem. 2012. PMID: 22213387 Free PMC article. No abstract available.

4

On terminal alkynes that can react with active-site cysteine nucleophiles in proteases.

Ekkebus R, van Kasteren SI, Kulathu Y, Scholten A, Berlin I, Geurink PP, de Jong A, Goerdayal S, Neefjes J, Heck AJ, Komander D, Ovaa H. Ekkebus R, et al. Among authors: geurink pp. J Am Chem Soc. 2013 Feb 27;135(8):2867-70. doi: 10.1021/ja309802n. Epub 2013 Feb 15. J Am Chem Soc. 2013. PMID: 23387960 Free PMC article.

5

Catching a DUB in the act: novel ubiquitin-based active site directed probes.

Ekkebus R, Flierman D, Geurink PP, Ovaa H. Ekkebus R, et al. Among authors: geurink pp. Curr Opin Chem Biol. 2014 Dec;23:63-70. doi: 10.1016/j.cbpa.2014.10.005. Curr Opin Chem Biol. 2014. PMID: 25461387 Free PMC article. Review.

6

Downregulation of 26S proteasome catalytic activity promotes epithelial-mesenchymal transition.

Banno A, Garcia DA, van Baarsel ED, Metz PJ, Fisch K, Widjaja CE, Kim SH, Lopez J, Chang AN, Geurink PP, Florea BI, Overkleeft HS, Ovaa H, Bui JD, Yang J, Chang JT. Banno A, et al. Among authors: geurink pp. Oncotarget. 2016 Apr 19;7(16):21527-41. doi: 10.18632/oncotarget.7596. Oncotarget. 2016. PMID: 26930717 Free PMC article.

7

Development of Diubiquitin-Based FRET Probes To Quantify Ubiquitin Linkage Specificity of Deubiquitinating Enzymes.

Geurink PP, van Tol BD, van Dalen D, Brundel PJ, Mevissen TE, Pruneda JN, Elliott PR, van Tilburg GB, Komander D, Ovaa H. Geurink PP, et al. Chembiochem. 2016 May 3;17(9):816-20. doi: 10.1002/cbic.201600017. Epub 2016 Mar 21. Chembiochem. 2016. PMID: 26996281 Free PMC article.

8

Non-hydrolyzable Diubiquitin Probes Reveal Linkage-Specific Reactivity of Deubiquitylating Enzymes Mediated by S2 Pockets.

Flierman D, van der Heden van Noort GJ, Ekkebus R, Geurink PP, Mevissen TE, Hospenthal MK, Komander D, Ovaa H. Flierman D, et al. Among authors: geurink pp. Cell Chem Biol. 2016 Apr 21;23(4):472-82. doi: 10.1016/j.chembiol.2016.03.009. Epub 2016 Apr 7. Cell Chem Biol. 2016. PMID: 27066941 Free PMC article.

9

The Molecular Basis for Ubiquitin and Ubiquitin-like Specificities in Bacterial Effector Proteases.

Pruneda JN, Durkin CH, Geurink PP, Ovaa H, Santhanam B, Holden DW, Komander D. Pruneda JN, et al. Among authors: geurink pp. Mol Cell. 2016 Jul 21;63(2):261-276. doi: 10.1016/j.molcel.2016.06.015. Epub 2016 Jul 14. Mol Cell. 2016. PMID: 27425412 Free PMC article.

10

Molecular basis of Lys11-polyubiquitin specificity in the deubiquitinase Cezanne.

Mevissen TET, Kulathu Y, Mulder MPC, Geurink PP, Maslen SL, Gersch M, Elliott PR, Burke JE, van Tol BDM, Akutsu M, Oualid FE, Kawasaki M, Freund SMV, Ovaa H, Komander D. Mevissen TET, et al. Among authors: geurink pp. Nature. 2016 Oct 20;538(7625):402-405. doi: 10.1038/nature19836. Epub 2016 Oct 12. Nature. 2016. PMID: 27732584 Free PMC article.

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